表单
liquid (Viscous Liquid or Paste)
质量水平
包含
200 ppm MEHQ
颜色
colorless to yellow
储存温度
−20°C
SMILES字符串
O=C(C(C)=C)NCCOCCOC(C)OCCOCCOCCOC(C)OCCOCCNC(C(C)=C)=O
InChI
1S/C26H48N2O10/c1-21(2)25(29)27-7-9-31-13-17-35-23(5)37-19-15-33-11-12-34-16-20-38-24(6)36-18-14-32-10-8-28-26(30)22(3)4/h23-24H,1,3,7-20H2,2,4-6H3,(H,27,29)(H,28,30)
InChI key
CQIHNSAQHHTPKN-UHFFFAOYSA-N
一般描述
Tri(ethylene glycol) (N-hydroxyethoxy)ethyl methacrylamide is a pH sensitive crosslinker and monomer containing an acetal group. The acetal group of the monomer is degraded upon acidic conditions and yields neutral degradation product. This monomer and crosslinker can be used in the synthesis of polyacetals which can be used in a variety of applications due to their instrinsically biodegradable properties. Additionally, they can exhibit (lower critical solution temperature) LCST behavior where they lose solubility upon heating.
应用
- Targeted drug delivery application
- Controlled or sustained drug delivery
- As a pH clevable crosslinker
- Polyacetal polymer synthesis
- Stimuli responsive hydrogels
特点和优势
- Unique degradation mechanism -Degrades in acidic condition and produces neutral degradation products
- Water soluble
- Biodegradable and biocompatible
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Polyacetals: Water-Soluble, pH-Degradable Polymers with Extraordinary Temperature Response
Samanta S, et al.
Macromolecules, 49, 1858?1864-1858?1864 (2016)
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