InChI
1S/C26H48N2O10/c1-21(2)25(29)27-7-9-31-13-17-35-23(5)37-19-15-33-11-12-34-16-20-38-24(6)36-18-14-32-10-8-28-26(30)22(3)4/h23-24H,1,3,7-20H2,2,4-6H3,(H,27,29)(H,28,30)
InChI key
CQIHNSAQHHTPKN-UHFFFAOYSA-N
SMILES string
O=C(C(C)=C)NCCOCCOC(C)OCCOCCOCCOC(C)OCCOCCNC(C(C)=C)=O
form
liquid (Viscous Liquid or Paste)
contains
200 ppm MEHQ
color
colorless to yellow
storage temp.
−20°C
Quality Level
General description
Tri(ethylene glycol) (N-hydroxyethoxy)ethyl methacrylamide is a pH sensitive crosslinker and monomer containing an acetal group. The acetal group of the monomer is degraded upon acidic conditions and yields neutral degradation product. This monomer and crosslinker can be used in the synthesis of polyacetals which can be used in a variety of applications due to their instrinsically biodegradable properties. Additionally, they can exhibit (lower critical solution temperature) LCST behavior where they lose solubility upon heating.
Application
- Targeted drug delivery application
- Controlled or sustained drug delivery
- As a pH clevable crosslinker
- Polyacetal polymer synthesis
- Stimuli responsive hydrogels
Features and Benefits
- Unique degradation mechanism -Degrades in acidic condition and produces neutral degradation products
- Water soluble
- Biodegradable and biocompatible
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Polyacetals: Water-Soluble, pH-Degradable Polymers with Extraordinary Temperature Response
Samanta S, et al.
Macromolecules, 49, 1858?1864-1858?1864 (2016)
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