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TissueFab®PODS Growth Factor Loaded Bioink Kit

Liver differentiation, (Gel)MA Vis/405nm

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description

Application(s): liver differentiation, cell culture, tissue engineering

form

viscous liquid

composition

PODS Human IGF-1, 25 µg , PODS Human Oncostatin M, 25 µg, 25 , PODS Human TNF-α, 25 µg , TissueFab GelMA bioink, Vis/405 nm low endotoxin

impurities

<5 cfu/mL Bioburden (Total Aerobic), <5 cfu/mL Bioburden (fungal), <50 EU/mL Endotoxin

color

colorless to pale yellow

pH

6.5-7.5

compatibility

(extrusion-based 3D bioprinting)

storage temp.

−20°C

General description

Rethink your bioinks with TissueFab®
About the material: The TissueFabtissu® PODS Growth Factor Loaded Bioink Kit, Liver differentiation, Vis/405 nm contains:
  • Low endotoxin gelatin-hylauronic acid based bioink
  • Human IGF-1 PODS®
  • Human Oncostatin M PODS®
  • Human TNF-α PODS®
Printing and crosslinking parameters:
  • Suitable for extrusion-based bioprinting
  • Visible light crosslinking at 405 nm wavelength
TissueFab PODS Growth Factor Loaded Bioink kit, Liver differentiation, (Gel)MA Vis/405nm is a ready-to-use bioink kit which is formulated for high cell viability, printing fidelity, and is designed for extrusion-based 3D bioprinting and subsequent crosslinking with exposure to 405nm visible light. TissueFab(R) PODS Growth Factor Loaded Bioink kit, Liver differentiation, (Gel)MA Vis/405nm can be used with most extrusion-based bioprinters, is biodegradable and cytocompatible. Included growth facors, Oncostatin M, IGF-1, and TNF-α, are known to play crucial roles in hepatocyte differentiation and proliferation as well as protection from hepatic lipotoxicity, inflammation, and fibrogenesis. Their inclusion with PODS delivery system allows their sustained release within bioprinted constructs and retainment of 70% bioactivity after 6 months. When mixed with the bioink component, the included PODS growth factors can promote hepatocyte differentiation of encapsulated cells. More information and a step by step protocol can be found under the "More Documents" section of this page.

Application

TissueFab PODS Growth Factor Loaded Bioink kit, Liver differentiation, Vis/405nm enables the precise fabrication of 3D hepatocyte models and tissue constructs for research in 3D cell biology, tissue engineering, in vitro tissue models, and regenerative medicine.

Features and Benefits

Key Features and Benefits: Each TissueFab® bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:

  • Printability and rheological properties
  • Crosslinking
  • Cell viability
  • Biocompatibility
  • Low bioburden
  • Low endotoxin
This product contains 10 ml of bioink solution and growth factors PODS® packaged separately to allow for optimization.

Legal Information

PODS is a registered trademark of Cell Guidance Systems Ltd
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 3

历史批次信息供参考:

分析证书(COA)

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