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Merck
CN

A0424

枸橼酸阿尔维林 柠檬酸盐

别名:

N-乙基-3,3′-二苯二丙胺

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关于此项目

经验公式(希尔记法):
C20H27N · C6H8O7
化学文摘社编号:
分子量:
473.56
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
226-929-3
MDL number:
Form:
powder
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form

powder

Quality Level

SMILES string

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CCCc1ccccc1)CCCc2ccccc2

InChI

1S/C20H27N.C6H8O7/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-8,11-14H,2,9-10,15-18H2,1H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

RYHCACJBKCOBTJ-UHFFFAOYSA-N

Gene Information

Application

Used for studies of pharmacological activity including:
  • Synergism with fluconazole against Saccharomyces cerevisiae and Candida albicans
  • Efficacy of combination with simeticone on abdominal pain associated with irritable bowel syndrome
  • Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
  • Drug effects viewed from a signal transduction network perspective
  • Enhanced cytotoxic effect of proteasome inhibitor MG132
  • Mechanism of action on phasic smooth muscles


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

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Engin Altintaş et al.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 19(3), 174-179 (2008-12-31)
Successful colonoscopy depends on the insertion of the instrument to the cecum, a detailed examination, and minimal discomfort to the patient during the procedure. The aim of this study was to determine the effects of alverine citrate plus simethicone on
Chinmoy Ghosh et al.
Drug testing and analysis, 2(6), 284-291 (2010-06-22)
A rapid and highly sensitive method for the determination of alverine (ALV) and its metabolite, para hydroxy alverine (PHA), in human plasma using LC-MS/MS in positive ion electrospray ionization (ESI) in multiple reactions monitoring (MRM) mode was developed and validated.
A general practice study to compare alverine citrate with mebeverine hydrochloride in the treatment of irritable bowel syndrome.
G J Tudor
The British journal of clinical practice, 40(7), 276-278 (1986-07-01)



全球贸易项目编号

货号GTIN
A0424-5G04061832854519