A47052
6-氨基屈
95%
别名:
7-胺基去乙酰氧基头胞烷酸
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关于此项目
经验公式（希尔记法）:
C18H13N
化学文摘社编号:
分子量:
243.30
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
220-149-7
MDL number:
Assay:
95%
Form:
solid
InChI key
KIVUHCNVDWYUNP-UHFFFAOYSA-N
InChI
1S/C18H13N/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H,19H2
SMILES string
Nc1cc2c3ccccc3ccc2c4ccccc14
assay
95%
form
solid
mp
209-211 °C (lit.)
Quality Level
Application
诱发小鼠肿瘤。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
K B Delclos et al.
Cancer research, 47(23), 6272-6277 (1987-12-01)
6-Nitrochrysene (NC) and 6-aminochrysene (AC) have been shown to be potent lung and liver carcinogens when administered in multiple i.p. doses to preweanling mice. 1,6-Dinitropyrene has been shown to be a strong hepatocarcinogen but a weak lung carcinogen in this
Yi Zhang et al.
Environmental toxicology and chemistry, 25(7), 1920-1925 (2006-07-13)
Chrysene is one of the basic polycyclic aromatic hydrocarbons that are toxic environmental pollutants. The photoproducts of 6-aminochrysene (6AC) include 5,6-chrysenequinone (5,6-CQ) along with some minor products. In this study, cytotoxicity and genotoxicity of 6AC and 5,6-CQ to a human
S M Morris et al.
Mutation research, 310(1), 45-54 (1994-10-01)
Cells from the human lymphoblastoid cell line, AHH-1, were exposed to two direct-acting mutagens, ethyl methanesulfonate (EMS) and ethyl nitrosourea (ENU), and to three carcinogens that require metabolic activation to an electrophile, benzo[a]pyrene (B(a)P), 6-aminochrysene (6-AC), and 6-nitrochrysene (6-NC); mutation
S Lahmy et al.
Toxicology, 29(4), 345-356 (1984-02-01)
By microspectrofluorimetry on single living cells (murine fibroblasts 3T3), we have obtained monoexponential decreases of fluorescence intensity for benzo[a]pyrene (B[a]P) and 6-aminochrysene (6a-chrysene) metabolism. These kinetics are characteristics of B[a]P and 6a-chrysene metabolism and histograms can be drawn from the
F K Friedman et al.
Pharmacology, 31(4), 194-202 (1985-01-01)
The microsomal cytochrome P-450-dependent aryl hydrocarbon hydroxylase is important in the detoxification of polycyclic hydrocarbons as well as their activation to cytotoxic or carcinogenic derivatives. We have studied compounds that can modify the activity of this enzyme system. Three types
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