Quality Level
assay
98%
form
solid
bp
160 °C/17 mmHg (lit.)
mp
56-58 °C (lit.)
SMILES string
NCC(O)c1ccccc1
InChI
1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2
InChI key
ULSIYEODSMZIPX-UHFFFAOYSA-N
Gene Information
human ... PNMT(5409)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Qian Wu et al.
Journal of medicinal chemistry, 48(23), 7243-7252 (2005-11-11)
The X-ray structure of human phenylethanolamine N-methyltransferase (hPNMT) complexed with its product, S-adenosyl-L-homocysteine (4), and the most potent inhibitor reported to date, SK&F 64139 (7), was used to identify the residues involved in inhibitor binding. Four of these residues, Val53
F Assimacopoulos-Jeannet et al.
Pflugers Archiv : European journal of physiology, 421(1), 52-58 (1992-05-01)
A beta-adrenergic agonist specific for brown adipose tissue, Ro 16-8714, was administered to control and obese insulin-resistant fa/fa rats and glucose utilisation measured in brown adipose tissue using the euglycaemic hyperinsulinaemic clamp combined with the injection of 2-deoxyglucose. Treatment with
Michail S Davidoff et al.
Histochemistry and cell biology, 124(3-4), 313-323 (2005-07-30)
Catecholamines play functional roles in the mature and developing mammalian testis but the cell types responsible for their local synthesis are still controversially discussed. Here, we demonstrate that four enzymes involved in the biosynthesis of catecholamines, namely, tyrosine hydroxylase (TH)
K M Buller et al.
Neuropharmacology, 49(2), 230-242 (2005-07-05)
In opiate addicts or patients receiving morphine treatment, it has been reported that the immune system is often compromised. The mechanisms responsible for the adverse effects of opioids on responses to infection are not clear but it is possible that
M Weinstock et al.
Neuropharmacology, 43(6), 999-1005 (2002-11-09)
TV-3326 is a novel cholinesterase inhibitor that produces irreversible brain-selective inhibition of monoamine oxidase (MAO)-A and B and has antidepressant-like activity in rats after chronic oral administration. This study determined whether TV-3326 would cause less potentiation than other irreversible MAO-inhibitors
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| A72405-50G | 04061832281469 |
| A72405-10G | 04061833383896 |
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