A72405
2-氨基-1-苯乙醇
98%
别名:
α-(氨基甲基)苄醇, DL-β-羟苯乙胺, 苯基乙醇胺
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关于此项目
线性分子式:
NH2CH2CH(OH)C6H5
化学文摘社编号:
分子量:
137.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
231-469-1
Beilstein/REAXYS Number:
971222
MDL number:
Assay:
98%
Form:
solid
InChI key
ULSIYEODSMZIPX-UHFFFAOYSA-N
InChI
1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2
SMILES string
NCC(O)c1ccccc1
assay
98%
form
solid
bp
160 °C/17 mmHg (lit.)
mp
56-58 °C (lit.)
Quality Level
Gene Information
human ... PNMT(5409)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Qian Wu et al.
Journal of medicinal chemistry, 48(23), 7243-7252 (2005-11-11)
The X-ray structure of human phenylethanolamine N-methyltransferase (hPNMT) complexed with its product, S-adenosyl-L-homocysteine (4), and the most potent inhibitor reported to date, SK&F 64139 (7), was used to identify the residues involved in inhibitor binding. Four of these residues, Val53
J P Revelli et al.
The Biochemical journal, 286 ( Pt 3), 743-746 (1992-09-15)
The number of beta 3-adrenergic receptors (AR) in plasma membranes from interscapular brown adipose tissue (IBAT) was decreased by 62% in lean Zucker rats treated with the thermogenic beta-adrenergic agonist Ro 16-8714 as compared with controls after 72 h of
M Landi et al.
Biochemical pharmacology, 44(4), 665-672 (1992-08-18)
[3H]Dihydroalprenolol ([3H]DHA) specific binding (determined by the difference in the presence and absence of 20 microM (-)isoprenaline) to rat colon membranes was saturable (Bmax = 39.6 fmol/mg protein), of high affinity (Kd = 0.87 nM) and stereospecific (IC50 330 and
Erkan Karakas et al.
Nature, 475(7355), 249-253 (2011-06-17)
Since it was discovered that the anti-hypertensive agent ifenprodil has neuroprotective activity through its effects on NMDA (N-methyl-D-aspartate) receptors, a determined effort has been made to understand the mechanism of action and to develop improved therapeutic compounds on the basis
C G Ziegler et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(37), 15879-15884 (2009-09-01)
Peptide analogues targeting various neuropeptide receptors have been used effectively in cancer therapy. A hallmark of adrenocortical tumor formation is the aberrant expression of peptide receptors relating to uncontrolled cell proliferation and hormone overproduction. Our microarray results have also demonstrated
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