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线性分子式:
NH2CH2CH(OH)C6H5
化学文摘社编号:
分子量:
137.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
231-469-1
Beilstein/REAXYS Number:
971222
MDL number:
Assay:
98%
Form:
solid
InChI key
ULSIYEODSMZIPX-UHFFFAOYSA-N
InChI
1S/C8H11NO/c9-6-8(10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2
SMILES string
NCC(O)c1ccccc1
assay
98%
form
solid
bp
160 °C/17 mmHg (lit.)
mp
56-58 °C (lit.)
Quality Level
Gene Information
human ... PNMT(5409)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
M Landi et al.
Biochemical pharmacology, 44(4), 665-672 (1992-08-18)
[3H]Dihydroalprenolol ([3H]DHA) specific binding (determined by the difference in the presence and absence of 20 microM (-)isoprenaline) to rat colon membranes was saturable (Bmax = 39.6 fmol/mg protein), of high affinity (Kd = 0.87 nM) and stereospecific (IC50 330 and
C G Ziegler et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(37), 15879-15884 (2009-09-01)
Peptide analogues targeting various neuropeptide receptors have been used effectively in cancer therapy. A hallmark of adrenocortical tumor formation is the aberrant expression of peptide receptors relating to uncontrolled cell proliferation and hormone overproduction. Our microarray results have also demonstrated
Erkan Karakas et al.
Nature, 475(7355), 249-253 (2011-06-17)
Since it was discovered that the anti-hypertensive agent ifenprodil has neuroprotective activity through its effects on NMDA (N-methyl-D-aspartate) receptors, a determined effort has been made to understand the mechanism of action and to develop improved therapeutic compounds on the basis
F Assimacopoulos-Jeannet et al.
Pflugers Archiv : European journal of physiology, 421(1), 52-58 (1992-05-01)
A beta-adrenergic agonist specific for brown adipose tissue, Ro 16-8714, was administered to control and obese insulin-resistant fa/fa rats and glucose utilisation measured in brown adipose tissue using the euglycaemic hyperinsulinaemic clamp combined with the injection of 2-deoxyglucose. Treatment with
Masashi Imanishi et al.
Journal of medicinal chemistry, 51(15), 4804-4822 (2008-07-25)
We designed a series of benzoic acid derivatives containing the biphenyl ether or biphenyl template on the RHS and a phenylethanolaminotetraline (PEAT) skeleton, which was prepared by highly stereoselective synthesis, to generate two structurally different lead compounds ( 10c, 10m)
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