A78608
2-氨基嘧啶
97%
别名:
2-嘧啶胺
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关于此项目
经验公式（希尔记法）:
C4H5N3
化学文摘社编号:
分子量:
95.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-648-4
Beilstein/REAXYS Number:
107014
MDL number:
产品名称
2-氨基嘧啶, 97%
InChI key
LJXQPZWIHJMPQQ-UHFFFAOYSA-N
InChI
1S/C4H5N3/c5-4-6-2-1-3-7-4/h1-3H,(H2,5,6,7)
SMILES string
Nc1ncccn1
assay
97%
form
powder
mp
122-126 °C (lit.)
Quality Level
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Robert J Altenbach et al.
Journal of medicinal chemistry, 51(20), 6571-6580 (2008-09-25)
A series of 2-aminopyrimidines was synthesized as ligands of the histamine H4 receptor (H4R). Working in part from a pyrimidine hit that was identified in an HTS campaign, SAR studies were carried out to optimize the potency, which led to
Manishkumar D Joshi et al.
Journal of chromatography. A, 1308, 161-165 (2013-08-21)
A reversed-phase high performance liquid chromatography (HPLC) method is described for the determination of boronic acids that are commonly present as impurities in pinacolboronate ester reagents. Boronic acids and their pinacolboronate esters are key reagents in the Suzuki-Miyaura coupling reaction.
Namrata Anand et al.
Bioorganic & medicinal chemistry, 20(17), 5150-5163 (2012-08-03)
A synthetic strategy to access small libraries of triazolylmethoxy chalcones 4{1-20}, triazolylmethoxy flavanones 5{1-10} and triazolylmethoxy aminopyrimidines 6{1-17} from a common substrate 4-propargyloxy-2-hydroxy acetophenone using a set of different reactions has been developed. The chalcones and flavanones were screened against
Jinho Lee et al.
Bioorganic & medicinal chemistry letters, 21(14), 4203-4205 (2011-06-21)
A series of new 2-(2-aminopyrimidin-4-yl)phenol derivatives were synthesized as potential antitumor compounds. Substitution with pyrrolidine-3,4-diol at the 4-position of phenol provided potent inhibitory activity against CDK1 and CDK2. X-ray crystal structural studies were performed to account for the effect of
Manuel Tzouros et al.
Chemical research in toxicology, 22(5), 853-862 (2009-03-26)
Covalent binding of reactive metabolites is generally accepted as one underlying mechanism of drug-induced toxicity. However, identification of protein targets by reactive metabolites still remains a challenge due to their low abundance. Here, we report the development of a highly
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