A78608
2-氨基嘧啶
97%
别名:
2-嘧啶胺
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关于此项目
经验公式（希尔记法）:
C4H5N3
化学文摘社编号:
分子量:
95.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
203-648-4
Beilstein/REAXYS Number:
107014
MDL number:
Assay:
97%
Form:
powder
InChI key
LJXQPZWIHJMPQQ-UHFFFAOYSA-N
InChI
1S/C4H5N3/c5-4-6-2-1-3-7-4/h1-3H,(H2,5,6,7)
SMILES string
Nc1ncccn1
assay
97%
form
powder
Quality Level
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Kamaljit Singh et al.
European journal of medicinal chemistry, 52, 82-97 (2012-03-31)
2-Aminopyrimidine based 4-aminoquinolines were synthesized using an efficacious protocol. Some of the compounds showed in vitro anti-plasmodial activity against drug-sensitive CQ(S) (3D7) and drug-resistant CQ(R) (K1) strains of Plasmodium falciparum in the nM range. In particular, 5-isopropyloxycarbonyl-6-methyl-4-(2-nitrophenyl)-2-[(7-chloroquinolin-4-ylamino)butylamino] pyrimidine depicted the lowest
Nicholas R Perl et al.
Journal of the American Chemical Society, 132(6), 1802-1803 (2010-01-26)
A convergent synthesis of (-)-crambidine is reported. The sequence capitalizes on two novel key transformations, including a [4+2] annulation of thioimidates with vinyl carbodiimides and an alkyne hydroamination employing 2-aminopyrimidine nucleophiles.
Ye-Xiang Xie et al.
The Journal of organic chemistry, 71(21), 8324-8327 (2006-10-10)
Efficient and solvent-free copper-catalyzed N-arylations of imidazoles with aryl and heteroaryl halides have been demonstrated. In the presence of CuBr, 2-aminopyrimidine-4,6-diol, and TBAF (n-Bu4NF), a variety of imidazoles underwent the N-arylation reaction with aryl and heteroaryl halides smoothly in moderate
D S Ermolat'ev et al.
Molecular diversity, 15(2), 491-496 (2010-08-27)
An efficient microwave-assisted one-pot two-step protocol was developed for the construction of disubstituted 2-amino-1H-imidazoles. This process involves the sequential formation of 2,3-dihydro-2-hydroxyimidazo[1,2-a]pyrimidinium salts from readily available 2-aminopyrimidines and α-bromoketones, followed by cleavage of the pyrimidine ring with hydrazine.
Manishkumar D Joshi et al.
Journal of chromatography. A, 1308, 161-165 (2013-08-21)
A reversed-phase high performance liquid chromatography (HPLC) method is described for the determination of boronic acids that are commonly present as impurities in pinacolboronate ester reagents. Boronic acids and their pinacolboronate esters are key reagents in the Suzuki-Miyaura coupling reaction.
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