A8309
乙酰肼
90%
别名:
Acetic acid hydrazide, Acetylhydrazine
方案
90%
表单
flakes
杂质
<10% acetic acid
沸点
129 °C/18 mmHg (lit.)
mp
58-68 °C (lit.)
SMILES字符串
CC(=O)NN
InChI
1S/C2H6N2O/c1-2(5)4-3/h3H2,1H3,(H,4,5)
InChI key
OFLXLNCGODUUOT-UHFFFAOYSA-N
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一般描述
乙酰肼是一种有机合成砌块，可通过催化氢化反应生成 N′-甲基乙酰肼(MAH)。
应用
乙酰乙肼可用于合成(E)-N′-（2-羟基亚苄基）乙酰肼，这是一种 ONO 钳形配体。
警示用语：
Danger
危险分类
Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Liquid phase hydrogenation of acethydrazone to N'-methyl acethydrazide over Pd/?-Al2O3 catalyst
Pakdehi SG, et al.
Brazilian Journal of Chemical Engineering, 27, 145-152 (2010)
A Walubo et al.
Methods and findings in experimental and clinical pharmacology, 20(8), 649-655 (1999-01-29)
Isoniazid and its metabolites acetylisoniazid, hydrazine and monoacetylhydrazine were investigated for generation of oxygen free radicals during incubation with rat liver slices. Lipid peroxidation was assessed by the thiobarbituric acid reactive substances test using malonaldehyde as the external standard, while
T C Sarich et al.
Archives of toxicology, 70(12), 835-840 (1996-01-01)
Isoniazid (INH) continues to be a highly effective drug in the chemoprophylaxis and treatment of tuberculosis; however, its use is associated with hepatotoxicity (predominantly hepatic necrosis) in 1-2% of individuals. The INH metabolites, acetylhydrazine and hydrazine, have each been implicated
Liquid phase hydrogenation of acethydrazone to N'-methyl acethydrazide over Pd/?-Al2O3 catalyst
Pakdehi SG, et al.
Brazilian Journal of Chemical Engineering, 27, 145-152 (2010)
Analysis of isoniazid, acetylhydrazine and [15N2]acetylhydrazine in serum by capillary gas chromatography-ammonia chemical ionization mass spectrometry.
G Karlaganis et al.
Journal of chromatography, 420(1), 171-177 (1987-09-04)
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