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线性分子式:
2-(H2N)C6H4CONH2
化学文摘社编号:
分子量:
136.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-851-2
Beilstein/REAXYS Number:
508509
MDL number:
Assay:
≥98%
Form:
crystals
InChI key
PXBFMLJZNCDSMP-UHFFFAOYSA-N
InChI
1S/C7H8N2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H2,9,10)
SMILES string
NC(=O)c1ccccc1N
assay
≥98%
form
crystals
fluorescence
λex 330 nm; λem 420 nm(lit.)
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Application
用于非选择性高效荧光标记聚糖。荧光标记灵敏度略低于邻氨基苯甲酸 (2-AA)。
荧光标记含有游离还原末端的聚糖。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
>365.0 °F
flash_point_c
> 185 °C
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Jessica Wohlgemuth et al.
Analytical biochemistry, 395(2), 178-188 (2009-08-25)
A common technique for analysis of protein glycosylation is HPLC coupled to mass spectrometry (LC-MS). However, analysis is challenging due to a low abundance of glycopeptides in complex protein digests, microheterogeneity at the glycosylation site, ion suppression effects, and competition
Bing Xia et al.
The Journal of organic chemistry, 78(5), 1994-2004 (2012-12-29)
As electrostatic equivalents of magnets, organic electrets offer unparalleled properties for impacting energy conversion and electronic applications. While biological systems have evolved to efficiently utilize protein α-helices as molecular electrets, the synthetic counterparts of these conjugates still remain largely unexplored.
Joomi Ahn et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(3-4), 403-408 (2009-12-29)
Separation by hydrophilic interaction chromatography (HILIC) with fluorescence detection utilizing a sub-2 microm glycan column for the separation of 2-aminobenzamide (2-AB) labeled N-linked glycans is described. The HILIC column packed with a 1.7 microm amide sorbent improves the peak capacity
Ada Triguero et al.
Analytical biochemistry, 400(2), 173-183 (2010-01-30)
Plants synthesize N-glycans containing the antigenic sugars alpha(1,3)-fucose and beta(1,2)-xylose. Therefore it is important to monitor these N-glycans in monoclonal antibodies produced in plants (plantibodies). We evaluated several techniques to characterize the N-glycosylation of a plantibody produced in tobacco plants
Jia Jia et al.
Organic & biomolecular chemistry, 10(31), 6279-6286 (2012-06-23)
Three fluorescent probes CdABA', CdABA and ZnABA', which are structural isomers of ZnABA, have been designed with N,N-bis(2-pyridylmethyl) ethylenediamine (BPEA) as chelator and 2-aminobenzamide as fluorophore. These probes can be divided into two groups: CdABA, CdABA' for Cd(2+) and ZnABA
商品
Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.
蛋白质的结构修饰对于活细胞是必不可少的。发生调节异常时,它们往往是会引发疾病。聚糖是生物系统中许多结构变异的原因,它们在细胞表面的表现通常被称为“糖”。
实验方案
Explore mass spectrometry analysis of glycans for glycomic & glycoproteomic neutral & acidic glycan analysis. See a general mass spec glycan analysis procedure.
该聚糖质谱分析方案,被称之为干液滴法,基于原始的MALDI实验并依然是MS领域中最常用的方法。
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