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线性分子式:
2-(H2N)C6H4CONH2
化学文摘社编号:
分子量:
136.15
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-851-2
Beilstein/REAXYS Number:
508509
MDL number:
Assay:
≥98%
Form:
crystals
产品名称
2-氨基苯甲酰胺, ≥98%
InChI key
PXBFMLJZNCDSMP-UHFFFAOYSA-N
InChI
1S/C7H8N2O/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H2,9,10)
SMILES string
NC(=O)c1ccccc1N
assay
≥98%
form
crystals
mp
111-113 °C (lit.)
fluorescence
λex 330 nm; λem 420 nm(lit.)
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Application
用于非选择性高效荧光标记聚糖。荧光标记灵敏度略低于邻氨基苯甲酸 (2-AA)。
荧光标记含有游离还原末端的聚糖。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
>365.0 °F
flash_point_c
> 185 °C
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Udayanath Aich et al.
The FEBS journal, 278(10), 1699-1712 (2011-03-18)
Agglutination of red blood cells (RBCs), including chicken RBCs (cRBCs), has been used extensively to estimate viral titer, to screen glycan-receptor binding preference, and to assess the protective response of vaccines. Although this assay enjoys widespread use, some virus strains
Elisabetta Soragni et al.
Journal of child neurology, 27(9), 1164-1173 (2012-07-06)
Numerous studies have pointed to histone deacetylase inhibitors as potential therapeutics for various neurodegenerative diseases, and clinical trials with several histone deacetylase inhibitors have been performed or are under way. However, histone deacetylase inhibitors tested to date either are highly
Nicolas Smargiasso et al.
Journal of the American Society for Mass Spectrometry, 23(3), 469-474 (2011-12-21)
One of the mechanisms leading to MALDI in-source decay (MALDI ISD) is the transfer of hydrogen radicals to analytes upon laser irradiation. Analytes such as peptides or proteins may undergo ISD and this method can therefore be exploited for top-down
Ada Triguero et al.
Analytical biochemistry, 400(2), 173-183 (2010-01-30)
Plants synthesize N-glycans containing the antigenic sugars alpha(1,3)-fucose and beta(1,2)-xylose. Therefore it is important to monitor these N-glycans in monoclonal antibodies produced in plants (plantibodies). We evaluated several techniques to characterize the N-glycosylation of a plantibody produced in tobacco plants
Joomi Ahn et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(3-4), 403-408 (2009-12-29)
Separation by hydrophilic interaction chromatography (HILIC) with fluorescence detection utilizing a sub-2 microm glycan column for the separation of 2-aminobenzamide (2-AB) labeled N-linked glycans is described. The HILIC column packed with a 1.7 microm amide sorbent improves the peak capacity
商品
Glycans play a key role in protein structure and disease; representation on cell surfaces is the glycome.
蛋白质的结构修饰对于活细胞是必不可少的。发生调节异常时,它们往往是会引发疾病。聚糖是生物系统中许多结构变异的原因,它们在细胞表面的表现通常被称为“糖”。
实验方案
Explore mass spectrometry analysis of glycans for glycomic & glycoproteomic neutral & acidic glycan analysis. See a general mass spec glycan analysis procedure.
该聚糖质谱分析方案,被称之为干液滴法,基于原始的MALDI实验并依然是MS领域中最常用的方法。
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