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Merck
CN

A9563

对氨基苯汞乙酸盐

≥90% (titration)

别名:

4-乙酸汞基苯胺, APMA

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关于此项目

线性分子式:
CH3CO2HgC6H4NH2
化学文摘社编号:
分子量:
351.75
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
228-497-1
Beilstein/REAXYS Number:
3664749
MDL number:
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Quality Level

assay

≥90% (titration)

form

powder

mp

163-165 °C (lit.)

solubility

DMSO: soluble 10 mg/mL, H2O: soluble 5 mM, glacial acetic acid: soluble 50 mg/mL

SMILES string

CC(=O)O[Hg]c1ccc(N)cc1

InChI

1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1

InChI key

RXSUFCOOZSGWSW-UHFFFAOYSA-M

Biochem/physiol Actions

基质金属蛋白酶的有机汞活化剂。

Disclaimer

对于美国客户:本品含汞。废弃后切勿放入垃圾桶,须按照地方、州或联邦法律处置。


signalword

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



历史批次信息供参考:

分析证书(COA)

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Jan-Olof Winberg et al.
European journal of biochemistry, 270(19), 3996-4007 (2003-09-27)
In the leukemic macrophage cell-line THP-1, a fraction of the secreted matrix metalloproteinase 9 (MMP-9) is linked to the core protein of chondroitin sulfate proteoglycans (CSPG). Unlike the monomeric and homodimeric forms of MMP-9, the addition of exogenous CaCl2 to
A Bianchi et al.
Osteoarthritis and cartilage, 24(11), 1961-1969 (2016-10-21)
Fibroblast Growth Factor 23 (FGF23) may represent an attractive candidate that could participate to the osteoarthritic (OA)-induced phenotype switch of chondrocytes. To address this hypothesis, we investigated the expression of FGF23, its receptors (FGFRs) and co-receptor (Klotho) in human cartilage
Reihane Ziadlou et al.
Biomolecules, 10(6) (2020-06-25)
In osteoarthritis (OA), inhibition of excessively expressed pro-inflammatory cytokines in the OA joint and increasing the anabolism for cartilage regeneration are necessary. In this ex-vivo study, we used an inflammatory model of human OA chondrocytes microtissues, consisting of treatment with



全球贸易项目编号

货号GTIN
A9563-5G04061833403570
A9563-25G04061833403556
A9563-1G04061824071207