所有图片(1)

文件

B10102

苯并[e]芘

Name: 苯并[<I>e</I>]芘
Brand: ALDRICH

98%

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所有图片(1)

别名:

1,2-苯并芘, 4,5-苯并芘

经验公式（希尔记法）:

C₂₀H₁₂

CAS号:

192-97-2

分子量:

252.31

Beilstein:

1911334

EC 号:

205-892-7

MDL编号:

MFCD00003605

PubChem化学物质编号:

24891539

NACRES:

NA.23

质量水平

100

检测方案

98%

形式

crystals

mp

177-180 °C (lit.)

SMILES字符串

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

InChI key

TXVHTIQJNYSSKO-UHFFFAOYSA-N

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一般描述

这种多环芳烃可溶于丙酮。它是一种非致癌的苯并芘异构体。研究显示，它在体内和体外暴露后无免疫抑制活性。在自然界中，它被秀丽隐杆线虫菌株代谢为3-苯并[e]芘硫酸盐、1-羟基-3-苯并[e]芘基硫酸盐和苯并[e]芘3-O-β-吡喃葡萄糖苷。

应用

用于研究苯并[e]芘对DNP-Ficoll和绵羊红细胞的抗体反应的免疫抑制活性以及从水样中提取有机化合物的“分散液-液微萃取”技术。

象形图

GHS08,GHS09

警示用语：

Danger

危险声明

H350 - H410

预防措施声明

P201 - P273 - P308 + P313

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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示例

T1503

货号

25G

包装规格/数量

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Determination of organic compounds in water using dispersive liquid-liquid microextraction.

Mohammad Rezaee et al.

Journal of chromatography. A, 1116(1-2), 1-9 (2006-04-01)

A new microextraction technique termed dispersive liquid-liquid microextraction (DLLME) was developed. DLLME is a very simple and rapid method for extraction and preconcentration of organic compounds from water samples. In this method, the appropriate mixture of extraction solvent (8.0 microL

Direct suppression of in vitro antibody production by mouse spleen cells by the carcinogen benzo(a)pyrene but not by the noncarcinogenic congener benzo(e)pyrene.

K L White et al.

Cancer research, 44(8), 3388-3393 (1984-08-01)

The role of metabolic activation of benzo(a)pyrene B(a)P in mediating its suppression of humoral immune responsiveness of the female C57BL/6 X C3H F1 (hereafter called B6C3F1) mouse was addressed in these studies. The model was the in vitro antibody response

Polycyclic aromatic hydrocarbons induce an inflammatory atherosclerotic plaque phenotype irrespective of their DNA binding properties.

Daniëlle M J Curfs et al.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(10), 1290-1292 (2005-06-09)

Although it has been demonstrated that carcinogenic environmental polycyclic aromatic hydrocarbons (PAHs) cause progression of atherosclerosis, the underlying mechanism remains unclear. In the present study, we aimed to investigate whether DNA binding events are critically involved in the progression of

Identification and characterization of a specific autoantiphosphatidylinositol immune response during the time course of benzo(a)pyrene-induced malignant tumors in female Sprague-Dawley rats.

S Faiderbe et al.

Cancer research, 52(10), 2862-2865 (1992-05-15)

High levels of anti-phosphatidylinositol (PtdIns) autoantibodies (autoAb) have been previously described in sera of cancer patients and in plasma of dimethylbenzanthracene-treated female Sprague-Dawley rats. The presence of anti-PtdIns autoAb was tested in a model of highly malignant sarcomas induced by

Induction of CYP1A1 gene expression in mouse hepatoma cells by benzo[e]pyrene, a ligand of the 4S polycyclic hydrocarbon-binding protein.

K Sterling et al.

Toxicology and applied pharmacology, 128(1), 18-24 (1994-09-01)

Hepa 1c1c7 (WT), TAOc1BPrc1 (CI), and BPrc1 (CII) mouse hepatoma cells were exposed to benzo[e]pyrene (B[e]P) or benzo[a]pyrene (B[a]P). B[e]P induced activity of a rat CYP1A1 reporter gene construct (-3015 to +2545 bp) by 1.8- to 2-fold and 5-fold in

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