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Merck
CN

B10102

苯并[e]芘

98%

别名:

1,2-苯并芘, 4,5-苯并芘

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关于此项目

经验公式(希尔记法):
C20H12
化学文摘社编号:
分子量:
252.31
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
205-892-7
Beilstein/REAXYS Number:
1911334
MDL number:
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产品名称

苯并[e]芘, 98%

InChI key

TXVHTIQJNYSSKO-UHFFFAOYSA-N

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

SMILES string

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

assay

98%

form

crystals

mp

177-180 °C (lit.)

Quality Level

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Application

用于研究苯并[e]芘对DNP-Ficoll和绵羊红细胞的抗体反应的免疫抑制活性 以及从水样中提取有机化合物的“分散液-液微萃取”技术。

General description

这种多环芳烃可溶于丙酮。它是一种非致癌的苯并芘异构体。 研究显示,它在体内和体外暴露后无免疫抑制活性。在自然界中,它被秀丽隐杆线虫菌株代谢为3-苯并[e]芘硫酸盐、1-羟基-3-苯并[e]芘基硫酸盐和苯并[e]芘3-O-β-吡喃葡萄糖苷。

pictograms

Health hazardEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mohammad Rezaee et al.
Journal of chromatography. A, 1116(1-2), 1-9 (2006-04-01)
A new microextraction technique termed dispersive liquid-liquid microextraction (DLLME) was developed. DLLME is a very simple and rapid method for extraction and preconcentration of organic compounds from water samples. In this method, the appropriate mixture of extraction solvent (8.0 microL
K L White et al.
Cancer research, 44(8), 3388-3393 (1984-08-01)
The role of metabolic activation of benzo(a)pyrene B(a)P in mediating its suppression of humoral immune responsiveness of the female C57BL/6 X C3H F1 (hereafter called B6C3F1) mouse was addressed in these studies. The model was the in vitro antibody response
Saffar Mansoor et al.
Investigative ophthalmology & visual science, 51(5), 2601-2607 (2009-12-05)
To study the inhibitory effects of some agents or drugs (inhibitors) on benzo(e)pyrene (B(e)P)-induced cell death and apoptosis on human retinal pigment epithelial (ARPE-19) cells in vitro. ARPE-19 cells were pretreated with varying concentrations of different classes of inhibitors (calpain
Narumi Sugihara et al.
Toxicology in vitro : an international journal published in association with BIBRA, 21(5), 827-834 (2007-04-06)
The previous studies from our laboratory reported that benzo(a)pyrene (Bap) influenced efflux transport of rhodamine 123 (Rho-123) by induction of P-glycoprotein (P-gp) in Caco-2 cells. The present study investigated whether induction of P-gp and the enhanced efflux transport of Rho-123
D F Lewis et al.
Toxicology letters, 71(3), 235-243 (1994-05-01)
The present studies were undertaken to provide a rationale for the observation that benzo(a)pyrene and 2-acetylaminofluorene induce the hepatic CYP1A1 protein, whereas their non-carcinogenic isomers benzo(e)pyrene and 4-acetylaminofluorene are, at best, relatively very weak inducers. Using amino acid sequence alignment

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