产品名称
γ-丁内酯, ReagentPlus®, ≥99%
InChI key
YEJRWHAVMIAJKC-UHFFFAOYSA-N
InChI
1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
SMILES string
O=C1CCCO1
vapor density
3 (vs air)
vapor pressure
1.5 mmHg ( 20 °C)
product line
ReagentPlus®
assay
≥99%
form
liquid
autoignition temp.
851 °F
expl. lim.
16 %
drug control
Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
refractive index
n20/D 1.436 (lit.)
bp
204-205 °C (lit.)
mp
−45 °C (lit.)
density
1.12 g/mL at 25 °C (lit.)
Quality Level
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Application
用于引入3-羧丙基侧链。用作电池和电容器中电解质溶液的组成成分。
Biochem/physiol Actions
γ-羟基丁酸(GHB)前体。 可通过阻断多巴胺能神经元的脉冲流,抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。
γ-羟基丁酸(GHB)前体;抑制多巴胺释放。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
target_organs
Central nervous system
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
208.4 °F - closed cup
flash_point_c
98 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
易制毒化学品(3类)
此项目有
Journal of Power Sources, 43, 195-195 (1993)
S Ohkawa et al.
Journal of medicinal chemistry, 34(1), 267-276 (1991-01-01)
A novel series of (3-pyridylmethyl)benzoquinone derivatives was molecular designed and synthesized for the dual purpose of inhibiting thromboxane A2 and leukotriene biosynthesis enzymes and scavenging active oxygen species (AOS). They were evaluated for inhibition of TXA2 synthase, inhibition of 5-lipoxygenase
Monica Blichowski et al.
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Infantile spasms (or IS) is a catastrophic childhood epilepsy that is particularly prevalent in children with Down syndrome. Previously, we have shown that the Ts65Dn (Ts) mouse model of Down syndrome is a useful substrate upon which to develop an
Jagan N Thupari et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(14), 9498-9502 (2002-06-13)
C75, a known inhibitor of fatty acid synthase is postulated to cause significant weight loss through decreased hypothalamic neuropeptide Y (NPY) production. Peripherally, C75, an alpha-methylene-gamma-butyrolactone, reduces adipose tissue and fatty liver, despite high levels of malonyl-CoA. To investigate this
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Journal of natural products, 76(2), 142-149 (2013-02-08)
Three novel hydrazides, geralcins C-E (1-3), were isolated from Streptomyces sp. LMA-545, together with MH-031 and geralcins A and B. This unusual family of compounds was isolated from liquid-state and agar-supported fermentation using Amberlite XAD-16 solid-phase extraction during the cultivation
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