B103608
γ-丁内酯
ReagentPlus®, ≥99%
别名:
γ-羟基丁酸内酯, 4-羟基丁酸内酯, GBL
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关于此项目
经验公式（希尔记法）:
C4H6O2
化学文摘社编号:
分子量:
86.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-509-5
Beilstein/REAXYS Number:
105248
MDL number:
Assay:
≥99%
Form:
liquid
InChI key
YEJRWHAVMIAJKC-UHFFFAOYSA-N
InChI
1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
SMILES string
O=C1CCCO1
vapor density
3 (vs air)
vapor pressure
1.5 mmHg ( 20 °C)
product line
ReagentPlus®
assay
≥99%
form
liquid
autoignition temp.
851 °F
expl. lim.
16 %
drug control
Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet
Quality Level
bp
204-205 °C (lit.)
mp
−45 °C (lit.)
density
1.12 g/mL at 25 °C (lit.)
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Application
用于引入3-羧丙基侧链。用作电池和电容器中电解质溶液的组成成分。
Biochem/physiol Actions
γ-羟基丁酸(GHB)前体。 可通过阻断多巴胺能神经元的脉冲流，抑制多巴胺释放。 γ-丁内酯预处理可用于检测自身受体诱导的多巴胺释放。
γ-羟基丁酸(GHB)前体；抑制多巴胺释放。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
target_organs
Central nervous system
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
208.4 °F - closed cup
flash_point_c
98 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
易制毒化学品（3类）
此项目有
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Journal of medicinal chemistry, 34(1), 267-276 (1991-01-01)
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Infantile spasms (or IS) is a catastrophic childhood epilepsy that is particularly prevalent in children with Down syndrome. Previously, we have shown that the Ts65Dn (Ts) mouse model of Down syndrome is a useful substrate upon which to develop an
Michelle Wood et al.
Journal of chromatography. A, 1056(1-2), 83-90 (2004-12-15)
We have developed a rapid method that enables the simultaneous analysis of gamma-hydroxybutyrate (GHB) and its precursors, i.e. gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in urine. The method comprised a simple dilution of the urine sample, followed by liquid chromatography-tandem mass
Christian Westendorf et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3853-3858 (2013-02-23)
The rapid reorganization of the actin cytoskeleton in response to external stimuli is an essential property of many motile eukaryotic cells. Here, we report evidence that the actin machinery of chemotactic Dictyostelium cells operates close to an oscillatory instability. When
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