方案
98%
表单
powder
mp
112-114 °C (lit.)
SMILES字符串
NNC(=O)c1ccccc1
InChI
1S/C7H8N2O/c8-9-7(10)6-4-2-1-3-5-6/h1-5H,8H2,(H,9,10)
InChI key
WARCRYXKINZHGQ-UHFFFAOYSA-N
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Warning
危险声明
危险分类
Acute Tox. 4 Oral - Carc. 2 - Skin Irrit. 2
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
E Agostinelli et al.
The Biochemical journal, 324 ( Pt 2), 497-501 (1997-06-01)
A novel copper-depleted bovine serum amine oxidase (BSAO), in which about half the molecules contained the organic cofactor in the oxidized form, was prepared by adding a reductant in anaerobic conditions to the cyanide-reacted protein. The CuI-semiquinone formed in these
M Kobayashi et al.
Biochemical and biophysical research communications, 256(2), 415-418 (1999-03-18)
The amidase from Rhodococcus rhodochrous J1, which hydrolyses amide to acid and ammonia, was found to catalyze the synthesis of hydrazide using hydrazine as a substrate. This is the first report on the hydrazide synthesis through enzymatic reactions. The enzyme
Susan M Aitken et al.
The Biochemical journal, 375(Pt 3), 613-621 (2003-07-19)
Many compounds are oxidized by haem enzymes, such as peroxidases and cytochromes P450, to highly reactive intermediates that function as enzyme inactivators. To evaluate the potential of arylhydrazides as selective metabolically activated peroxidase inhibitors, the mechanism of HRPC (horseradish peroxidase
Tetsuya Toya et al.
Bioorganic & medicinal chemistry, 10(4), 953-961 (2002-02-12)
We have investigated the biologically active conformation of the non-steroidal ecdysone agonist, 1-tert-butyl-1,2-dibenzoylhydrazine (RH-5849) by means of design, synthesis and conformational analysis of cyclic derivatives of RH-5849. Among the synthesized compounds, a 6-membered cyclic hydrazine bearing two benzoyl groups (5)
Venkataswamy Sorna et al.
Journal of medicinal chemistry, 56(23), 9496-9508 (2013-11-19)
Lysine specific demethylase 1 (LSD1) plays an important role in regulating histone lysine methylation at residues K4 and K9 on histone H3 and is an attractive therapeutic target in multiple malignancies. Here we report a structure-based virtual screen of a
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