B38503
双(2-氯乙基)胺 盐酸盐
98%
别名:
β,β′-二氯乙基胺盐酸盐, 1,5-二氯-3-氮杂戊烷盐酸盐, 2,2′-Di氯乙基胺盐酸盐, 2-氯-N-(2-氯乙基)乙胺盐酸盐, N,N-双(2-氯乙基)胺盐酸盐, 二(2-氯乙基)胺盐酸盐, 双(β-氯乙基)胺盐酸盐, 双(2-氯乙基)氯化铵, 双(2-氯乙基)胺盐酸盐, 盐酸氮芥Nornitrogen mustard hydrochloride
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关于此项目
线性分子式:
(ClCH2CH2)2NH·HCl
化学文摘社编号:
分子量:
178.49
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-479-5
Beilstein/REAXYS Number:
3550356
MDL number:
Assay:
98%
Form:
powder
产品名称
双(2-氯乙基)胺 盐酸盐, 98%
InChI key
YMDZDFSUDFLGMX-UHFFFAOYSA-N
InChI
1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H
SMILES string
Cl.ClCCNCCCl
assay
98%
form
powder
mp
212-214 °C (lit.)
Quality Level
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General description
双(2-氯乙基)胺盐酸盐可作为起始材料合成哌嗪衍生物。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
No information available.
flash_point_c
No information available.
ppe
dust mask type N95 (US), Eyeshields, Gloves
Joanna Cytarska et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 27(3), 303-311 (2019-04-13)
Synthesis, characterization and investigation of antiproliferative activity of nine triazene salts against human cancer cells lines (MV-4-11, MCF-7, JURKAT, HT-29, Hep-G2, HeLa, Du-145 and DAUDI), and normal human mammary epithelial cell line (MCF7-10A) is presented. The structures of novel compounds
Basic principles in preclinical cancer chemotherapy.
N Brock et al.
Journal of cancer research and clinical oncology, 116(5), 411-424 (1990-01-01)
Daan Noort et al.
Archives of toxicology, 76(2), 83-88 (2002-03-27)
Covalent binding of various clinically important nitrogen mustards to the cysteine-34 residue of human serum albumin, in vitro and in vivo, is demonstrated. A rapid method for detection of these adducts is presented, based on liquid chromatography-tandem mass spectrometry analysis
R Fleer et al.
Chemico-biological interactions, 39(1), 1-15 (1982-03-01)
Activated cyclophosphamide (CP) is known to achieve its cytotoxic and alkylating capacity upon spontaneous hydrolytic breakdown of the oxazaphosphorine ring structure. Treatment of yeast cells with the chemically activated form of CP (4-hydroperoxy-CP, 4-OOH-CP) and with several potentially toxic cleavage
H Thulin et al.
Toxicology and industrial health, 11(1), 89-97 (1995-01-01)
Nor-nitrogen mustard is an alkylating agent used in kilogram quantities in the production of various cytostatics. It has been shown to be mutagenic in vitro, and therefore must be regarded as a health hazard. We have studied the environment and
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