B38503
双(2-氯乙基)胺 盐酸盐
98%
别名:
β,β′-二氯乙基胺盐酸盐, 1,5-二氯-3-氮杂戊烷盐酸盐, 2,2′-Di氯乙基胺盐酸盐, 2-氯-N-(2-氯乙基)乙胺盐酸盐, N,N-双(2-氯乙基)胺盐酸盐, 二(2-氯乙基)胺盐酸盐, 双(β-氯乙基)胺盐酸盐, 双(2-氯乙基)氯化铵, 双(2-氯乙基)胺盐酸盐, 盐酸氮芥Nornitrogen mustard hydrochloride
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关于此项目
线性分子式:
(ClCH2CH2)2NH·HCl
化学文摘社编号:
分子量:
178.49
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-479-5
Beilstein/REAXYS Number:
3550356
MDL number:
Assay:
98%
Form:
powder
Quality Level
assay
98%
form
powder
mp
212-214 °C (lit.)
SMILES string
Cl.ClCCNCCCl
InChI
1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H
InChI key
YMDZDFSUDFLGMX-UHFFFAOYSA-N
General description
双(2-氯乙基)胺盐酸盐可作为起始材料合成哌嗪衍生物。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
No information available.
flash_point_c
No information available.
ppe
dust mask type N95 (US), Eyeshields, Gloves
Joanna Cytarska et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 27(3), 303-311 (2019-04-13)
Synthesis, characterization and investigation of antiproliferative activity of nine triazene salts against human cancer cells lines (MV-4-11, MCF-7, JURKAT, HT-29, Hep-G2, HeLa, Du-145 and DAUDI), and normal human mammary epithelial cell line (MCF7-10A) is presented. The structures of novel compounds
S Papot et al.
Bioorganic & medicinal chemistry letters, 10(16), 1835-1837 (2000-09-02)
A new glucuronylated prodrug of nornitrogen mustard, incorporating the same spacer group as the doxorubicin prodrug HMR 1826, has been prepared. Upon exposure to E. coli beta-glucuronidase, fast hydrolysis occurs but a lower cytotoxicity against LoVo cancer cells is observed
K Hemminki
Chemico-biological interactions, 61(1), 75-88 (1987-01-01)
Nornitrogen mustard was shown to bind to the N-7 position of guanine in DNA and guanosine. The initial binding product was NOR-G. N-(2-chloroethyl)-N-[2-(7-guaninyl)ethyl]amine but it was converted with time to a hydroxylated derivative. NOR-OH-G and to a cross-link, G-NOR-G. The
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| B38503-25G | 04061833428511 |
| B38503-250G | 04061832763811 |
| B38503-100G | 04061833428504 |