B38503
双(2-氯乙基)胺 盐酸盐
98%
别名:
β,β′-二氯乙基胺盐酸盐, 1,5-二氯-3-氮杂戊烷盐酸盐, 2,2′-Di氯乙基胺盐酸盐, 2-氯-N-(2-氯乙基)乙胺盐酸盐, N,N-双(2-氯乙基)胺盐酸盐, 二(2-氯乙基)胺盐酸盐, 双(β-氯乙基)胺盐酸盐, 双(2-氯乙基)氯化铵, 双(2-氯乙基)胺盐酸盐, 盐酸氮芥Nornitrogen mustard hydrochloride
质量水平
方案
98%
表单
powder
mp
212-214 °C (lit.)
SMILES字符串
Cl.ClCCNCCCl
InChI
1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H
InChI key
YMDZDFSUDFLGMX-UHFFFAOYSA-N
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一般描述
双(2-氯乙基)胺盐酸盐可作为起始材料合成哌嗪衍生物。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
储存分类代码
8A - Combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
No information available.
闪点(°C)
No information available.
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Joanna Cytarska et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 27(3), 303-311 (2019-04-13)
Synthesis, characterization and investigation of antiproliferative activity of nine triazene salts against human cancer cells lines (MV-4-11, MCF-7, JURKAT, HT-29, Hep-G2, HeLa, Du-145 and DAUDI), and normal human mammary epithelial cell line (MCF7-10A) is presented. The structures of novel compounds
H Thulin et al.
Toxicology and industrial health, 11(1), 89-97 (1995-01-01)
Nor-nitrogen mustard is an alkylating agent used in kilogram quantities in the production of various cytostatics. It has been shown to be mutagenic in vitro, and therefore must be regarded as a health hazard. We have studied the environment and
R Fleer et al.
Chemico-biological interactions, 39(1), 1-15 (1982-03-01)
Activated cyclophosphamide (CP) is known to achieve its cytotoxic and alkylating capacity upon spontaneous hydrolytic breakdown of the oxazaphosphorine ring structure. Treatment of yeast cells with the chemically activated form of CP (4-hydroperoxy-CP, 4-OOH-CP) and with several potentially toxic cleavage
Daan Noort et al.
Archives of toxicology, 76(2), 83-88 (2002-03-27)
Covalent binding of various clinically important nitrogen mustards to the cysteine-34 residue of human serum albumin, in vitro and in vivo, is demonstrated. A rapid method for detection of these adducts is presented, based on liquid chromatography-tandem mass spectrometry analysis
Basic principles in preclinical cancer chemotherapy.
N Brock et al.
Journal of cancer research and clinical oncology, 116(5), 411-424 (1990-01-01)
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