B38503
双(2-氯乙基)胺 盐酸盐
98%
别名:
β,β′-二氯乙基胺盐酸盐, 1,5-二氯-3-氮杂戊烷盐酸盐, 2,2′-Di氯乙基胺盐酸盐, 2-氯-N-(2-氯乙基)乙胺盐酸盐, N,N-双(2-氯乙基)胺盐酸盐, 二(2-氯乙基)胺盐酸盐, 双(β-氯乙基)胺盐酸盐, 双(2-氯乙基)氯化铵, 双(2-氯乙基)胺盐酸盐, 盐酸氮芥Nornitrogen mustard hydrochloride
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关于此项目
线性分子式:
(ClCH2CH2)2NH·HCl
化学文摘社编号:
分子量:
178.49
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-479-5
Beilstein/REAXYS Number:
3550356
MDL number:
Assay:
98%
Form:
powder
InChI key
YMDZDFSUDFLGMX-UHFFFAOYSA-N
InChI
1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H
SMILES string
Cl.ClCCNCCCl
assay
98%
form
powder
mp
212-214 °C (lit.)
Quality Level
General description
双(2-氯乙基)胺盐酸盐可作为起始材料合成哌嗪衍生物。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
No information available.
flash_point_c
No information available.
ppe
dust mask type N95 (US), Eyeshields, Gloves
Joanna Cytarska et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 27(3), 303-311 (2019-04-13)
Synthesis, characterization and investigation of antiproliferative activity of nine triazene salts against human cancer cells lines (MV-4-11, MCF-7, JURKAT, HT-29, Hep-G2, HeLa, Du-145 and DAUDI), and normal human mammary epithelial cell line (MCF7-10A) is presented. The structures of novel compounds
E Kruse et al.
Pharmacology & toxicology, 64(1), 9-13 (1989-01-01)
To further clarify the mode of action of estramustine, the influence on macromolecular synthesis in the human prostatic tumour cell line 1013L was investigated. Cell treatment with estramustine, nor-nitrogen mustard and tauromustine, followed by radioactive nucleotide and leucine incorporations, as
B Hartley-Asp
The Prostate, 5(1), 93-100 (1984-01-01)
In growth proliferation experiments on two human prostatic carcinoma cell lines, DU 145 cells were found to be more sensitive to the cytotoxic effect of estramustine and nor-nitrogen mustard than PC-3 cells. Estramustine was, however, much more cytotoxic in both
G Momerency et al.
Biological mass spectrometry, 23(3), 149-158 (1994-03-01)
A method is described for the determination of the antitumour drug cyclophosphamide and six stable metabolites in plasma of cancer patients, namely dechloroethyl-cyclophosphamide, 4-keto-cyclophosphamide, carboxy-phosphamide, alcophosphamide, nor-nitrogen mustard and the N-chloroethyl-1,3-oxazolidine-2-one, as methyl and/or trifluoroacetyl derivatives by single ion monitoring
B Hartley-Asp et al.
The Journal of urology, 127(4), 818-822 (1982-04-01)
Estramustine at concentrations ranging from 3-40 x 10(-6) M inhibited the cell growth and clonogenic survival of a human prostatic carcinoma cell line (DU 145). This cell line was found to be unresponsive to estradiol and testosterone at concentrations ranging
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