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Merck
CN

C11006

碳酰肼

98%

别名:

1,3-二氨基脲, N,N′-二氨基脲, 碳酰二肼, 碳酰肼

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关于此项目

线性分子式:
CO(NHNH2)2
化学文摘社编号:
分子量:
90.08
Beilstein:
1747069
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

98%

表单

crystals

mp

150-153 °C (lit.)

SMILES字符串

NNC(=O)NN

InChI

1S/CH6N4O/c2-4-1(6)5-3/h2-3H2,(H2,4,5,6)

InChI key

XEVRDFDBXJMZFG-UHFFFAOYSA-N

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应用

碳酰肼用于:
  • 作为除氧剂。
  • 通过缩合反应,与各种醛和配体合成多齿席夫碱配体。
  • 通过环缩合反应合成含三氟甲基的(E)-N′--亚芳基-1-H-吡唑-1-碳酰肼,具有抗氧化剂和抗菌特性。

象形图

Exclamation markEnvironment

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1

补充剂危害

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marta Kisiel et al.
Journal of controlled release : official journal of the Controlled Release Society, 162(3), 646-653 (2012-08-21)
Understanding the influence of formulation and storage conditions on rhBMP-2 bioactivity is extremely important for its clinical application. Reports in the literature show that different research groups employ different parameters such as formulation conditions, storage, doses for in vivo applications
Ameen Ali Abu-Hashem et al.
Acta pharmaceutica (Zagreb, Croatia), 60(3), 311-323 (2010-12-08)
2-Amino-5-acetyl-4-methyl-thiophene-3-carboxylic acid ethyl ester (1) and 5-acetyl-2-amino-4-methylthiophene-3-carbohydrazide (2) were synthesized and used as starting materials for the synthesis of new series of 1-(5-amino-4-(3,5-dimethyl-1H-pyrazole-1-carbonyl)-3-methylthiophen-2-yl) ethanone (3a), 1-(5-amino-4-(4-chloro-3,5-dimethyl-1H-pyrazole-1-carbonyl)-3-methylthiophen-2-yl) ethanone (3b), 1-(4-methyl-2-amino-5-acetylthiophene-3-carbonyl)pyrazolidine-3,5-dione (4), (Z)-N'-(4-methyl-2-amino-5-acetylthiophene-3-carbonyl) formohydrazonic acid (5a), (Z)-ethyl-N'-4-methyl-2-amino-5-acetylthiophene-3-carbonylformo hydrazonate (5b), 6-acetyl-3-amino-2,5-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (8), 5-methyl-3-amino-2-mercapto-6-acetylthieno
Alessandro K Jordão et al.
Bioorganic & medicinal chemistry, 19(18), 5605-5611 (2011-08-16)
Tuberculosis treatment remains a challenge that requires new antitubercular agents due to the emergence of multidrug-resistant Mycobacterium strains. This paper describes the synthesis, the antitubercular activity and the theoretical analysis of N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides (8a-b, 8e-f, 8i-j and 8n-o) and new analogues
Paolo Mombelli et al.
ChemMedChem, 7(1), 151-158 (2011-11-19)
A series of inhibitors of plant enzymes of the non-mevalonate pathway from herbicide research efforts at BASF were screened for antimalarial activity in a cell-based assay. A 1,3-diiminoisoindoline carbohydrazide was found to inhibit the growth of Plasmodium falciparum with an
New trifluoromethyl-containing (E)-N?-arylidene-[3-alkyl (aryl/heteroaryl)-4, 5-dihydro-1H-pyrazol-1-yl] carbohydrazides: Synthesis, crystal structure and antimicrobial/antioxidant activity.
Bonacorso HG, et al.
Journal of Fluorine Chemistry, 135(10), 303-314 (2012)

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