Merck
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安全信息

C121908

Sigma-Aldrich

L-半胱氨酸乙酯 盐酸盐

98%

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别名:
(R)-Ethyl 2-amino-3-mercaptopropanoate hydrochloride, Cystanin, Ethyl L-cysteinate hydrochloride
线性分子式:
HSCH2CH(NH2)COOC2H5 · HCl
CAS号:
868-59-7
分子量:
185.67
Beilstein:
3562600
EC 号:
212-779-6
MDL编号:
MFCD00012631
eCl@ss:
32160406
PubChem化学物质编号:
24892386
NACRES:
NA.22

质量水平

200

检测方案

98%

形式

powder

旋光性

[α]20/D −7.9°, c = 1 in 1 M HCl

光学纯度

ee: 99% (GLC)

反应适用性

reaction type: solution phase peptide synthesis

颜色

white

mp

123-125 °C (lit.)

应用

peptide synthesis

SMILES字符串

Cl[H].CCOC(=O)[C@@H](N)CS

InChI

1S/C5H11NO2S.ClH/c1-2-8-5(7)4(6)3-9;/h4,9H,2-3,6H2,1H3;1H/t4-;/m0./s1

InChI key

JFKJWWJOCJHMGV-WCCKRBBISA-N

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相关类别

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

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Krum Kafedjiiski et al.
International journal of pharmaceutics, 343(1-2), 48-58 (2007-06-05)
It was the aim of this study to synthesize and characterize a novel hyaluronic acid-cysteine ethyl ester (HA-Cys) conjugate providing improved mucoadhesive properties and a significantly lowered biodegradation rate. Mediated by carbodiimide and N-hydroxysuccinimide, L-cysteine ethyl ester hydrochloride was covalently
Dimitrios Tsikas et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(28), 3442-3455 (2009-07-15)
S-Nitrosothiols from low-molecular-mass and high-molecular-mass thiols, including glutathione, albumin and hemoglobin, are endogenous potent vasodilators and inhibitors of platelet aggregation. By utilizing the S-transnitrosation reaction and by using the lipophilic (pK(L) 0.78) and strong nucleophilic synthetic thiol N-acetyl cysteine ethyl
Dimitrios Galanakis et al.
Bioorganic & medicinal chemistry letters, 14(14), 3639-3643 (2004-06-19)
The synthesis and pharmacological evaluation of a series of amide derivatives of NSAIDs with L-cysteine ethyl ester is described. The novel derivatives are potent antiinflammatory, antioxidant and hypocholesterolemic-hypolipidemic agents, while they demonstrate considerably reduced gastrointestinal toxicity. This molecular modification may
Seema A Kattaya et al.
Clinical orthopaedics and related research, 466(8), 1796-1803 (2008-05-20)
Gamma radiation is widely used to sterilize bone allografts but may impair their strength. While radioprotectant use may reduce radiation damage they may compromise sterility by protecting pathogens. We assessed the radioprotective potential of various agents (L-cysteine, N-acetyl-L-cysteine, L-cysteine-ethyl-ester and
Laura L Perissinotti et al.
Journal of the American Chemical Society, 127(2), 486-487 (2005-01-13)
We report an investigation of the reaction between (S)-nitroso-l-cysteine ethyl ester and l-cysteine ethyl ester as a model of physiologically relevant transnitrosation processes. Our theoretical and experimental evidence clearly supports the existence of a nitroxyl disulfide intermediate in solution.
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