D108103
1,8-二羟基蒽醌
96%
别名:
丹蒽醌, 二羟蒽醌
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关于此项目
经验公式（希尔记法）:
C14H8O4
化学文摘社编号:
分子量:
240.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-173-5
Beilstein/REAXYS Number:
2054727
MDL number:
InChI key
QBPFLULOKWLNNW-UHFFFAOYSA-N
InChI
1S/C14H8O4/c15-9-5-1-3-7-11(9)14(18)12-8(13(7)17)4-2-6-10(12)16/h1-6,15-16H
SMILES string
Oc1cccc2C(=O)c3cccc(O)c3C(=O)c12
assay
96%
form
powder
Gene Information
human ... RXRA(6256)
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Application
1,8-二羟基蒽醌可用于：
- 制备β-环糊精包合物，用作水溶液中Cu2+估计的传感器。
- 作为1,4,5,8-四甲氧基蒽合成的起始材料。
- 在木质素修饰中用作芳基清除剂，木质素可作为钢的缓蚀剂。
signalword
Warning
hcodes
Hazard Classifications
Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
No data available
flash_point_c
No data available
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
A Practical Synthesis of 1, 4, 5, 8-Tetramethoxyanthracene from Inexpensive and Readily Available 1, 8-Dihydroxyanthraquinone
Navale TS and Rathore R
Synthesis, 44(05), 805-809 (2012)
Improved corrosion inhibition of mild steel by chemically modified lignin polymers from Elaeis guineensis agricultural waste
Hussin MH, et al.
Materials Chemistry and Physics, 163(05), 201-212 (2015)
Yong-Soo Kwon et al.
Biological & pharmaceutical bulletin, 27(5), 723-726 (2004-05-11)
Oxidative stress caused by an elevation in reactive oxygen species (ROS) plays an important role in Alzheimer's disease and other neurodegenerative diseases. In this study, we examined the neuroprotective effect of danthron (1,8-dihydroxyanthraquinone) against neurotoxicities induced by beta-amyloid (25-35), excitotoxins
Jo-Hua Chiang et al.
Chemical research in toxicology, 24(1), 20-29 (2010-12-04)
Anthraquinones have been shown to induce apoptosis in different types of tumor cells, but the mechanisms of danthron-induced cytotoxicity and apoptosis in human gastric cancer cells have not been adequately explored. This study investigated the roles of caspase cascades, ROS
Haitao Zhang et al.
The Journal of biological chemistry, 286(3), 1868-1875 (2010-11-19)
Retinoic X receptor (RXR) is a promising target for drug discovery against cancer and metabolic syndromes. Here, we identified a specific RXRα antagonist, danthron, from the traditional Chinese medicine rhubarb. Danthron repressed all tested RXRα-involved response element transcription, including the
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