Merck
CN

D126608

Sigma-Aldrich

丙泊酚

97%

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别名:
2,6-双(1-甲基乙基)苯酚, 2,6-双(异丙基)苯酚, 丙泊酚
线性分子式:
[(CH3)2CH]2C6H3OH
CAS号:
分子量:
178.27
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

蒸汽压

5.6 mmHg ( 100 °C)

质量水平

检测方案

97%

形式

liquid

折射率

n20/D 1.514 (lit.)

bp

256 °C/764 mmHg (lit.)

mp

18 °C (lit.)

密度

0.962 g/mL at 25 °C (lit.)

SMILES string

CC(C)c1cccc(C(C)C)c1O

InChI

1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3

InChI key

OLBCVFGFOZPWHH-UHFFFAOYSA-N

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此商品
PHR1663BP1031Y0000017
2,6-Diisopropylphenol 97%

Sigma-Aldrich

D126608

丙泊酚

Propofol Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1663

丙泊酚

Propofol British Pharmacopoeia (BP) Reference Standard

BP1031

普鲁泊福

Propofol for peak identification European Pharmacopoeia (EP) Reference Standard

Y0000017

普鲁泊福

form

liquid

form

-

form

-

form

-

refractive index

n20/D 1.514 (lit.)

refractive index

n20/D 1.514 (lit.)

refractive index

n20/D 1.514 (lit.)

refractive index

n20/D 1.514 (lit.)

bp

256 °C/764 mmHg (lit.)

bp

256 °C/764 mmHg (lit.)

bp

256 °C/764 mmHg (lit.)

bp

256 °C/764 mmHg (lit.)

mp

18 °C (lit.)

mp

18 °C (lit.)

mp

18 °C (lit.)

mp

18 °C (lit.)

density

0.962 g/mL at 25 °C (lit.)

density

0.962 g/mL at 25 °C (lit.)

density

0.962 g/mL at 25 °C (lit.)

density

0.962 g/mL at 25 °C (lit.)

一般描述

2,6-二异丙基苯酚(一种强疏水取代苯酚)是一种新型静脉麻醉剂。已研究 2,6-二异丙基苯酚(异丙酚)的抗氧化属性。2,6-二异丙基苯酚是一种有效的静脉注射催眠药,广泛用于麻醉诱导和维持以及重症监护病房的镇静。用于全身麻醉的诱导和维持。

应用

2,6-二异丙基苯酚是研究其对离体大鼠肝线粒体氧化磷酸化作用的合适试剂。是制备双(2,6-二异丙基苯氧基)双(2-甲基-8-喹啉)钛 (IV) 配合物的合适试剂。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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2-tert-Butyl-6-methyl-phenol 99%

Sigma-Aldrich

B97607

2-叔丁基-6-甲基苯酚

2-Isopropylbenzenethiol technical grade, 90%

Sigma-Aldrich

I27503

2-异丙基苯硫酚

vibrant-m

Y0000018

丙泊酚杂质J

2,6-Dimethylphenol 99%

Sigma-Aldrich

D175005

2,6-二甲基苯酚

P G Murphy et al.
British journal of anaesthesia, 68(6), 613-618 (1992-06-01)
We have examined in vitro the antioxidant properties of 2,6-diisopropylphenol. In studies using electron spin resonance spectroscopy we have demonstrated that 2,6-diisopropylphenol acts as an antioxidant by reacting with free radicals to form a phenoxyl radical--a property common to all
M Rigoulet et al.
European journal of biochemistry, 241(1), 280-285 (1996-10-01)
We investigated the effects of 2,6-diisopropylphenol on oxidative phosphorylation of isolated rat liver mitochondria. Diisopropylphenol strongly inhibits state-3 and uncoupled respiratory rates, when glutamate and malate are the substrates, as a direct consequence of the limitation of electron transfer at
Configurational rearrangements in cis-M (AA)2X2, cis-M (AA)2XY, and cis-M(AB)2X2 complexes.
Bickley DG and Serpone N.
Inorganic Chemistry, 18(8), 2200-2204 (1979)
C Frenkel et al.
European journal of pharmacology, 208(1), 75-79 (1991-09-12)
Single sodium channels from human brain cortex tissue were incorporated into voltage-clamped planar lipid bilayers in the presence of batrachotoxin and studied with various doses of the new anaesthetic compound propofol (2,6-diisopropylphenol). Propofol was found to depress two major sodium
Paul E Marik
Current pharmaceutical design, 10(29), 3639-3649 (2004-12-08)
Propofol (2, 6-diisopropylphenol) is a potent intravenous hypnotic agent which is widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. Propofol is an oil at room temperature and insoluble in aqueous solution.

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