D126608
普鲁泊福
97%
别名:
2,6-双(1-甲基乙基)苯酚, 普鲁泊福
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线性分子式:
[(CH3)2CH]2C6H3OH
化学文摘社编号:
分子量:
178.27
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
218-206-6
MDL number:
产品名称
普鲁泊福, 97%
InChI key
OLBCVFGFOZPWHH-UHFFFAOYSA-N
InChI
1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
SMILES string
CC(C)c1cccc(C(C)C)c1O
vapor pressure
5.6 mmHg ( 100 °C)
assay
97%
form
liquid
refractive index
n20/D 1.514 (lit.)
bp
256 °C/764 mmHg (lit.)
mp
18 °C (lit.)
density
0.962 g/mL at 25 °C (lit.)
Quality Level
Gene Information
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Application
2,6-二异丙基苯酚是研究其对离体大鼠肝线粒体氧化磷酸化作用的合适试剂。是制备双（2,6-二异丙基苯氧基）双（2-甲基-8-喹啉）钛 (IV) 配合物的合适试剂。
General description
2,6-二异丙基苯酚（一种强疏水取代苯酚）是一种新型静脉麻醉剂。已研究 2,6-二异丙基苯酚（异丙酚）的抗氧化属性。2,6-二异丙基苯酚是一种有效的静脉注射催眠药，广泛用于麻醉诱导和维持以及重症监护病房的镇静。用于全身麻醉的诱导和维持。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
235.4 °F - closed cup
flash_point_c
113 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Paul E Marik
Current pharmaceutical design, 10(29), 3639-3649 (2004-12-08)
Propofol (2, 6-diisopropylphenol) is a potent intravenous hypnotic agent which is widely used for the induction and maintenance of anesthesia and for sedation in the intensive care unit. Propofol is an oil at room temperature and insoluble in aqueous solution.
Configurational rearrangements in cis-M (AA)2X2, cis-M (AA)2XY, and cis-M(AB)2X2 complexes.
Bickley DG and Serpone N.
Inorganic Chemistry, 18(8), 2200-2204 (1979)
C Frenkel et al.
European journal of pharmacology, 208(1), 75-79 (1991-09-12)
Single sodium channels from human brain cortex tissue were incorporated into voltage-clamped planar lipid bilayers in the presence of batrachotoxin and studied with various doses of the new anaesthetic compound propofol (2,6-diisopropylphenol). Propofol was found to depress two major sodium
P G Murphy et al.
British journal of anaesthesia, 68(6), 613-618 (1992-06-01)
We have examined in vitro the antioxidant properties of 2,6-diisopropylphenol. In studies using electron spin resonance spectroscopy we have demonstrated that 2,6-diisopropylphenol acts as an antioxidant by reacting with free radicals to form a phenoxyl radical--a property common to all
M Rigoulet et al.
European journal of biochemistry, 241(1), 280-285 (1996-10-01)
We investigated the effects of 2,6-diisopropylphenol on oxidative phosphorylation of isolated rat liver mitochondria. Diisopropylphenol strongly inhibits state-3 and uncoupled respiratory rates, when glutamate and malate are the substrates, as a direct consequence of the limitation of electron transfer at
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