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线性分子式:
(CH3)2NCOCl
化学文摘社编号:
分子量:
107.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-208-6
Beilstein/REAXYS Number:
878197
MDL number:
Assay:
98%
Form:
liquid
InChI
1S/C3H6ClNO/c1-5(2)3(4)6/h1-2H3
InChI key
YIIMEMSDCNDGTB-UHFFFAOYSA-N
SMILES string
CN(C)C(Cl)=O
assay
98%
form
liquid
refractive index
n20/D 1.453 (lit.)
bp
167-168 °C/775 mmHg (lit.)
mp
−33 °C (lit.)
density
1.168 g/mL at 25 °C (lit.)
Quality Level
Application
二甲基氨基甲酰氯可用于合成:
- 苄基苯酚中的双取代氨基甲酸酯。
- 通过与异烟酸 N -氧化物和氰化锌反应生成2-氰基异烟酰胺。采用该方法合成一种新型黄嘌呤氧化还原酶抑制剂。
- 乙酰胆碱酯酶 (AChE) 和 5-羟色胺转运体 (SERT) 双重抑制剂。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
179.6 °F - closed cup
flash_point_c
82 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
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A E Hochwalt et al.
Molecular carcinogenesis, 1(1), 4-6 (1988-01-01)
Rat nasal squamous cell carcinomas induced by inhalation of three direct-acting alkylating agents yielded DNA containing activated oncogenes with no homology to any member of the ras family. The novel NIH 3T3 transforming oncogenes from tumors induced by beta-propiolactone and
S J Garte et al.
Environmental health perspectives, 81, 29-31 (1989-05-01)
Techniques of molecular biology have been used to determine the relationship of cellular oncogenes to mechanisms of experimental carcinogenesis. Model systems involving three direct-acting alkylating carcinogens, two organ sites, and two species have been employed to elucidate the relationships between
Dimethylcarbamoyl chloride.
IARC monographs on the evaluation of carcinogenic risks to humans, 71 Pt 2, 531-543 (1999-09-07)
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