D218200
5,5′-二硫代双（2-硝基苯甲酸）
ReagentPlus®, 99%
别名:
6,6′-二硝基-3,3′-二硫代苯甲酸, DTNB, Ellman 试剂, 二硫代硝基苯甲酸, 双(3-羧基-4-硝基苯基)二硫
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关于此项目
线性分子式:
[-SC6H3(NO2)CO2H]2
化学文摘社编号:
分子量:
396.35
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-714-4
Beilstein/REAXYS Number:
1896821
MDL number:
产品名称
5,5′-二硫代双（2-硝基苯甲酸）, ReagentPlus®, 99%
InChI key
KIUMMUBSPKGMOY-UHFFFAOYSA-N
InChI
1S/C14H8N2O8S2/c17-13(18)9-5-7(1-3-11(9)15(21)22)25-26-8-2-4-12(16(23)24)10(6-8)14(19)20/h1-6H,(H,17,18)(H,19,20)
SMILES string
OC(=O)c1cc(SSc2ccc(c(c2)C(O)=O)[N+]([O-])=O)ccc1[N+]([O-])=O
product line
ReagentPlus®
assay
99%
form
powder
mp
240-245 °C (dec.) (lit.)
Quality Level
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Application
5,5′-二硫代双(2-硝基苯甲酸)是一种水溶性试剂，主要用于巯基的衍生化。
General description
DTNB (Ellman’s 试剂) 常用于蛋白质和生物分子中巯基 (thiol) 的定量测定。
Legal Information
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Determination of thiols and disulfides via HPLC quantification of 5-thio-2-nitrobenzoic acid
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Previous structures of Arp2/3 complex, determined in the absence of a nucleation-promoting factor and actin, reveal its inactive conformation. The study of the activated structure has been hampered by uncontrollable polymerization. We have engineered a stable activated complex consisting of
Anne Bertling et al.
Arteriosclerosis, thrombosis, and vascular biology, 32(8), 1979-1990 (2012-04-28)
Staphylococcus aureus can induce platelet aggregation. The rapidity and degree of this correlates with the severity of disseminated intravascular coagulation, and depends on platelet peptidoglycans. Surface-located thiol isomerases play an important role in platelet activation. The staphylococcal extracellular adherence protein
Atef M K Nassar et al.
Molecules (Basel, Switzerland), 25(11) (2020-06-11)
Sumithion (Fenitrothion) (SUM) is an organophosphorus insecticide used to combat a wide variety of plant pests. Exposure to SUM causes significant toxicity to the brain, liver, kidney, and reproductive organs through, for example, binding to DNA, and it induces DNA
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