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D26202

3,5-二氨基-1,2,4-三氮唑

Name: 3,5-二氨基-1,2,4-三氮唑
Brand: ALDRICH

98%

别名:

胍唑

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关于此项目

经验公式（希尔记法）:

C₂H₅N₅

化学文摘社编号:

1455-77-2

分子量:

99.09

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24893699

EC Number:

215-937-2

Beilstein/REAXYS Number:

112467

MDL number:

MFCD00005233

Assay:

98%

Form:

solid

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属性

Quality Level

200

assay

98%

form

solid

mp

202-205 °C (lit.)

SMILES string

Nc1n[nH]c(N)n1

InChI

1S/C2H5N5/c3-1-5-2(4)7-6-1/h(H5,3,4,5,6,7)

InChI key

PKWIYNIDEDLDCJ-UHFFFAOYSA-N

说明

General description

3,5-二氨基-1,2,4-三唑，别名胍唑，是杂环化合物，常作为合成砌块制备叔丁基取代无环和环状化合物的镓络合物。也用作铜的缓蚀剂。

Application

DNA 合成抑制剂。

pictograms

GHS08,GHS09

signalword

Warning

hcodes

H361fd,H373,H411

pcodes

P202 - P260 - P273 - P280 - P308 + P313 - P391

Hazard Classifications

Aquatic Chronic 2 - Repr. 2 - STOT RE 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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DNA repair induced by various mutagens in rat hepatocyte primary cultures measured in the presence of hydroxyurea, guanazole or aphidicolin.

W Suter et al.

Mutation research, 231(2), 251-264 (1990-08-01)

Guanazole and aphidicolin were chosen as candidates in the search for a selective, non-genotoxic inhibitor of DNA replication which could be used instead of hydroxyurea to measure DNA repair synthesis in rat hepatocyte primary cultures by liquid scintillation counting. The

Studies on the differential mechanisms of inhibition of ribonucleotide reductase by specific inhibitors of the non-heme iron subunit.

A Sato et al.

Advances in enzyme regulation, 22, 231-241 (1984-01-01)

The data presented here show that while the non-heme iron subunit of ribonucleotide reductase is inhibited by IMPY, hydroxyurea and MAIQ, the mechanism of inhibition by hydroxyurea and IMPY is distinct from that for MAIQ. This difference in mechanisms is

Molecular geometry and vibrational studies of 3,5-diamino-1,2,4-triazole using quantum chemical calculations and FT-IR and FT-Raman spectroscopies.

L Guennoun et al.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 78(1), 347-353 (2010-11-30)

The 3,5-diamino-1,2,4-triazole (guanazole) was investigated by vibrational spectroscopy and quantum methods. The solid phase FT-IR and FT-Raman spectra were recorded in the region 4000-400 cm(-1) and 3600-50 cm(-1) respectively, and the band assignments were supported by deuteration effects. The results

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全球贸易项目编号

货号	GTIN
D26202-100G	04061838353856
D26202-25G	04061833562444