D26202
3,5-二氨基-1,2,4-三氮唑
98%
别名:
胍唑
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关于此项目
经验公式（希尔记法）:
C2H5N5
化学文摘社编号:
分子量:
99.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
215-937-2
Beilstein/REAXYS Number:
112467
MDL number:
Assay:
98%
Form:
solid
InChI
1S/C2H5N5/c3-1-5-2(4)7-6-1/h(H5,3,4,5,6,7)
InChI key
PKWIYNIDEDLDCJ-UHFFFAOYSA-N
SMILES string
Nc1n[nH]c(N)n1
assay
98%
form
solid
mp
202-205 °C (lit.)
Quality Level
General description
3,5-二氨基-1,2,4-三唑，别名胍唑，是杂环化合物，常作为合成砌块制备叔丁基取代无环和环状化合物的镓络合物。也用作铜的缓蚀剂。
Application
DNA 合成抑制剂。
signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 2 - Repr. 2 - STOT RE 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
G Tipples et al.
Journal of bacteriology, 173(16), 4932-4940 (1991-08-01)
Chlamydiae are obligate intracellular bacteria that are dependent on eukaryotic host cells for ribonucleoside triphosphates but not deoxyribonucleotide triphosphates. Ribonucleotide reductase is the only enzyme known to catalyze the direct conversion of a ribonucleotide to a deoxyribonucleotide. Hydroxyurea inhibits ribonucleotide
R G Hards et al.
Journal of cellular physiology, 106(2), 309-319 (1981-02-01)
We describe the isolation and characterization of a Chinese hamster ovary cell line selected for resistance to N-carbamoyloxyurea. Using the mammalian cell permeabilization assay developed in our laboratory, a detailed analysis of the target enzyme, ribonucleotide reductase (EC 1.17.4.1), was
Studies on the selective toxicity of guanazole in mice.
C Dave et al.
European journal of cancer, 14(1), 33-40 (1978-01-01)
[Pharmacokinetics of antitumor drugs].
V A Filov et al.
Voprosy onkologii, 29(7), 3-13 (1983-01-01)
Inhibition of ribonucleotide reductases encoded by herpes simplex viruses.
T Spector
Pharmacology & therapeutics, 31(3), 295-302 (1985-01-01)
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