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Merck
CN

D3511

Sigma-Aldrich

反式-4,5-二羟基-1,2-二噻烷

greener alternative

≥99%

别名:

反式-1,2-二噻烷-4,5-二醇, 氧化 DTT

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关于此项目

经验公式(希尔记法):
C4H8O2S2
化学文摘社编号:
分子量:
152.24
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案

≥99%

表单

powder

环保替代产品得分

old score: 9
new score: 6
Find out more about DOZN™ Scoring

环保替代产品特性

Atom Economy
Less Hazardous Chemical Syntheses
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

130-132 °C (lit.)

环保替代产品分类

储存温度

2-8°C

SMILES字符串

O[C@@H]1CSSC[C@H]1O

InChI

1S/C4H8O2S2/c5-3-1-7-8-2-4(3)6/h3-6H,1-2H2/t3-,4-/m1/s1

InChI key

YPGMOWHXEQDBBV-QWWZWVQMSA-N

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一般描述

反式 -4,5-二羟基-1,2-二噻烷(氧化 dtt)是二硫苏糖醇的分子内二硫键形式。它是一种强还原剂,能够通过激活应激反应基因引发分子应激反应。
我们竭诚为您带来满足绿色替代产品四大类别要求的替代产品。该产品属于再设计产品类别,在“原子经济性”、“危险性较小的化学合成”和“使用可再生原料”绿色化学原则方面取得了重大改进。 点击此处查看其 DOZN 记分卡。

其他说明

二硫苏糖醇 (DTT) 的氧化型。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Modulating the endoplasmic reticulum stress response with trans-4, 5-dihydroxy-1, 2-dithiane prevents chemically induced renal injury in vivo.
Asmellash S
Toxicological Sciences, 88(2), 576-584 (2005)
Zimai Li et al.
Antioxidants (Basel, Switzerland), 9(10) (2020-10-18)
Reactive sulfane sulfur, including persulfide and polysulfide, is a type of regular cellular component, playing an antioxidant role. Its function may be organelle-dependent; however, the shortage of probes for detecting organellar reactive sulfane sulfur has hindered further investigation. Herein, we
Hélène Launay et al.
Journal of molecular biology, 430(8), 1218-1234 (2018-03-05)
Among intrinsically disordered proteins, conditionally disordered proteins undergo dramatic structural disorder rearrangements upon environmental changes and/or post-translational modifications that directly modulate their function. Quantifying the dynamics of these fluctuating proteins is extremely challenging but paramount to understanding the regulation of
Francesca Sparla et al.
Plant physiology, 141(3), 840-850 (2006-05-16)
Nine genes of Arabidopsis (Arabidopsis thaliana) encode for beta-amylase isozymes. Six members of the family are predicted to be extrachloroplastic isozymes and three contain predicted plastid transit peptides. Among the latter, chloroplast-targeted beta-amylase (At4g17090) and thioredoxin-regulated beta-amylase (TR-BAMY; At3g23920; this
Reduction of trans-4, 5-Dihydroxy-1, 2-dithiane by Cellular Oxidoreductases Activates gadd153/chop and grp78 Transcription and Induces Cellular Tolerance in Kidney Epithelial Cells.
Halleck MM
The Journal of Biological Chemistry, 272(35), 21760-21766 (1997)

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