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D5431

2-(N,N-二乙基氨基)-二氮烯-2-氧 二乙铵盐

≥98%

别名:

DEA NONOate, DEA/无二乙基铵盐

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关于此项目

线性分子式:
(CH3CH2)2N–N(N=O)O- (CH3CH2)2NH2+
化学文摘社编号:
372965-00-9
分子量:
206.29
NACRES:
NA.22
PubChem Substance ID:
329798805
UNSPSC Code:
12352116
MDL number:
MFCD00216152
Assay:
≥98%
Form:
solid
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description

t1/2 16 min phosphate buffer, 22 °C NO release

assay

≥98%

form

solid

shipped in

dry ice

storage temp.

−70°C

SMILES string

CCNCC.CCN(CC)N(O)N=O

InChI

1S/C4H11N3O2.C4H11N/c1-3-6(4-2)7(9)5-8;1-3-5-4-2/h9H,3-4H2,1-2H3;5H,3-4H2,1-2H3

InChI key

LBJLVZKEUWCGIA-UHFFFAOYSA-N

Application

DEA/NO二乙基铵盐可以用作：        
  • 一氧化氮 (NO) 供体。
  • 用于Wilkinson′s催化剂还原亚硝基化的试剂

用作：
  • 威尔金森还原亚硝基化试剂催化剂
  • 一氧化氮 (NO) 供体

Biochem/physiol Actions

NO 供体

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

监管及禁止进口产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCK9803
SLCH3638
SLCD6671
SLCB8130
SLBS2808V

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商品

Sensor Dyes

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.

感应染料

一氧化氮 (NO) 是神经元、内皮细胞和免疫系统中的信号转运分子。

Xi Ye et al.
The Journal of physiology, 596(16), 3553-3566 (2018-06-05)
Prolonged exposure to vascular endothelial growth factor A (VEGF-A) inhibits agonist-mediated endothelial cell Ca2+ release and subsequent activation of intermediate conductance Ca2+ -activated K+ (IKCa ) channels, which underpins vasodilatation as a result of endothelium-dependent hyperpolarization (EDH) in mouse resistance
Xin Zhang et al.
The Journal of biological chemistry, 277(50), 48472-48478 (2002-10-09)
4,5-Diaminofluorescein (DAF-2) is widely used for detection and imaging of NO based on its sensitivity, noncytotoxicity, and specificity. In the presence of oxygen, NO and NO-related reactive nitrogen species nitrosate 4,5-diaminofluorescein to yield the highly fluorescent DAF-2 triazole (DAF-2T). However
Joseph C Galley et al.
Molecular pharmacology, 95(6), 629-637 (2019-04-17)
Nitric oxide (NO) stimulates soluble guanylyl cyclase (sGC) activity, leading to elevated intracellular cyclic guanosine 3',5'-monophosphate (cGMP) and subsequent vascular smooth muscle relaxation. It is known that downregulation of sGC expression attenuates vascular dilation and contributes to the pathogenesis of
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全球贸易项目编号

货号GTIN
D5431-50MG04061833586235