所有图片(1)

文件

D64600

5,7-二氯-8-羟基喹啉

Name: 5,7-二氯-8-羟基喹啉
Brand: ALDRICH

99%

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别名:

5,7-二氯-8-羟基氮杂萘, 氯喔星

经验公式（希尔记法）:

C₉H₅Cl₂NO

CAS号:

773-76-2

分子量:

214.05

EC 号:

212-258-3

MDL编号:

MFCD00006786

PubChem化学物质编号:

24894028

NACRES:

NA.22

质量水平

100

检测方案

99%

形式

powder

mp

178-180 °C (lit.)

SMILES字符串

Oc1c(Cl)cc(Cl)c2cccnc12

InChI

1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

InChI key

WDFKMLRRRCGAKS-UHFFFAOYSA-N

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象形图

GHS05,GHS07

警示用语：

Danger

危险声明

H302 - H315 - H318 - H335

预防措施声明

P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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示例

T1503

货号

25G

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A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions.

Luying Xun et al.

The Journal of biological chemistry, 279(8), 6696-6700 (2003-12-10)

Ralstonia eutropha JMP134 2,4,6-trichlorophenol (2,4,6-TCP) 4-monooxygenase catalyzes sequential dechlorinations of 2,4,6-TCP to 6-chlorohydroxyquinol. Although 2,6-dichlorohydroxyquinol is a logical metabolic intermediate, the enzyme hardly uses it as a substrate, implying it may not be a true intermediate. Evidence is provided to

Validation of a UPLC-PDA method to study the content and stability of 5-chloro 8-hydroxyquinoline and 5,7-dichloro 8-hydroxyquinoline in medicated feed used in swine farming.

Miriam Aide Castillo Rodríguez et al.

Journal of pharmaceutical and biomedical analysis, 166, 113-118 (2019-01-15)

A new, rapid, simple and specific method to determine 5-chloro 8-hydroxyquinoline (5-HQ) and 5,7-dichloro 8-hydroxyquinoline (5,7-HQ) stability in swine feed was optimized and validated. A system consisting of an ACQUITY UPLC BEH C18 column (1.7 μm, 2.1 mm × 100 mm), a mobile phase of

[Clinical evaluation on the usefulness of 5,7-dichloro-8-hydroxyquinoline (chloroxine) in association with betamethasone 17-benzoate in the topical treatment of infected cortisone-sensitive dermopathies].

M Negosanti et al.

Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 120(2), XVII-XXIII (1985-03-01)

Effects of chlorhexidine, iodine, and 5,7-dichloro-8-hydroxyquinoline on the bacterial composition of rat plaque in vivo.

M J Schaeken et al.

Caries research, 18(5), 440-446 (1984-01-01)

Reverse-phase high-performance liquid chromatographic determination of halogenated 8-hydroxyquinoline compounds in pharmaceuticals and bulk drugs.

E J Wojtowicz

Journal of pharmaceutical sciences, 73(10), 1430-1433 (1984-10-01)

A reverse-phase high-performance liquid chromatographic (HPLC) method was developed for determining iodochlorhydroxyquin, 5,7-dichloro-8-hydroxyquinoline, and 5,7-diiodo-8-hydroxyquinoline in creams, ointments, shampoos, tablets, and bulk drugs. A column packed with 10-micron phenyl-silica and a mobile phase of 0.001 M NiCl2 in acetonitrile-methanol-water (30:20:50)

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