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Merck
CN

D8765

Sigma-Aldrich

乙胺嗪 柠檬酸盐

≥98%

别名:

1-二乙胺基甲酰基-4-甲基哌嗪 柠檬酸盐

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关于此项目

线性分子式:
C10H21N3O · C6H8O7
化学文摘社编号:
分子量:
391.42
Beilstein:
3836352
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
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方案

≥98%

表单

powder

抗生素抗菌谱

parasites

作用机制

enzyme | inhibits

SMILES字符串

OC(=O)CC(O)(CC(O)=O)C(O)=O.CCN(CC)C(=O)N1CCN(C)CC1

InChI

1S/C10H21N3O.C6H8O7/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-9H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key

PGNKBEARDDELNB-UHFFFAOYSA-N

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象形图

Skull and crossbones

警示用语:

Danger

危险声明

危险分类

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Koneni V Sashidhara et al.
Bioorganic & medicinal chemistry letters, 22(4), 1527-1532 (2012-01-31)
A series of 3,6-epoxy [1,5]dioxocines were synthesized and evaluated for their antifilarial activity against adult parasites of human lymphatic filarial parasite Brugia malayi (sub-periodic strain) in vitro. Out of these, six compounds (4a-f) possessed improved in vitro anti-filarial activity and
B K Singh et al.
European journal of medicinal chemistry, 43(12), 2717-2723 (2008-03-15)
A series of 2-sulfanyl-6-methyl-1,4-dihydropyrimidines (8-21) were synthesized in good yields by alkylation of 5-methyl-6-phenyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid ethyl esters (2-7) with different alkyl or aralkyl halides in the presence of a combination of anhydrous K(2)CO(3) and catalytic amount of tetrabutyl ammonium bromide.
Gary O Rankin et al.
Toxicology, 300(1-2), 92-99 (2012-06-19)
The agricultural fungicide N-(3,5-dichlorophenyl)succinimide (NDPS) can induce marked nephrotoxicity in rats following a single intraperitoneal (ip) administration of 0.4mmol/kg or greater. Although NDPS induces direct renal proximal tubular toxicity, a role for renal vascular effects may also be present. The
Ana Wládia Lima et al.
Revista da Sociedade Brasileira de Medicina Tropical, 45(6), 745-750 (2013-01-09)
The Global Programme to Eliminate Lymphatic Filariasis was launched with the goal of eliminating this disease via the annual mass drug administration (MDA) of a single dose of antifilarial drugs. Adverse drug reactions following MDA are a major factor of
Cathy Steel et al.
PLoS neglected tropical diseases, 6(12), e1940-e1940 (2012-12-14)
Antibody (Ab) to the Wuchereria bancrofti (Wb) infective larval (L3) antigen Wb123, using a Luciferase Immunoprecipitation System (LIPS) assay, has been shown to be a species-specific, early marker of infection developed for potential use as a surveillance tool following transmission

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