F4043
漆黄素
≥98%
别名:
3,3′,4′,7-四羟基黄酮, 紫铆素, 非瑟素
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关于此项目
经验公式(希尔记法):
C15H10O6 · xH2O
化学文摘社编号:
分子量:
286.24 (anhydrous basis)
颜色索引号:
75620
Beilstein:
292829
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
方案
≥98%
mp
>330 °C (lit.)
储存温度
−20°C
SMILES字符串
O.Oc1ccc2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3
InChI
1S/C15H10O6.H2O/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7;/h1-6,16-18,20H;1H2
InChI key
GYHFUROKCOMWNQ-UHFFFAOYSA-N
基因信息
human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), GSK3A(2931)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835)
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一般描述
漆黄素是一种膳食黄酮类化合物,存在于多种水果和蔬菜中。它具有抗癌、抗炎、抗氧化活性,还具有记忆增强功能。
应用
漆黄素可用于:
- 制备其强抗氧化活性的铁金属配合物。
- 通过分析工具研究其与环糊精(α和β)的相互作用。
非瑟酮是一种天然存在的具有治疗活性的黄酮醇,用于合成具有药物活性的抗炎、抗惊厥和抗增殖药物。
其他说明
存在于许多木本植物中的棕色颜料
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity.
Zheng, Long Tai and Ock, Jiyeon and Kwon, Byoung-Mog and Suk, Kyoungho
International Immunopharmacology, 8(3), 484-494 (2008)
Fisetin: a dietary antioxidant for health promotion
Khan N, et al.
Antioxidants & Redox Signaling, 19(2), 151-162 (2013)
Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin
Funakoshi-Tago M, et al.
International Immunopharmacology, 11(9), 1150-1159 (2011)
Mohammed Alsuraih et al.
JHEP reports : innovation in hepatology, 3(3), 100250-100250 (2021-04-20)
Cholangiocyte senescence is important in the pathogenesis of primary sclerosing cholangitis (PSC). We found that CDKN2A (p16), a cyclin-dependent kinase inhibitor and mediator of senescence, was increased in cholangiocytes of patients with PSC and from a PSC mouse model (multidrug
Xu Sun et al.
International journal of molecular medicine, 42(2), 811-820 (2018-05-12)
Fisetin, a natural flavonoid found in a variety of edible and medical plants, has been suggested to inhibit the proliferation of various tumor cells and to induce apoptosis. However, the effects of fisetin on breast cancer have rarely been reported
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