F4043
漆黄素
≥98%
别名:
3,3′,4′,7-四羟基黄酮, 紫铆素, 非瑟素
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关于此项目
经验公式（希尔记法）:
C15H10O6 · xH2O
化学文摘社编号:
分子量:
286.24 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
Colour Index Number:
75620
EC Number:
208-434-4
MDL number:
Beilstein/REAXYS Number:
292829
assay
≥98%
mp
>330 °C (lit.)
storage temp.
−20°C
SMILES string
O.Oc1ccc2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3
InChI
1S/C15H10O6.H2O/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7;/h1-6,16-18,20H;1H2
InChI key
GYHFUROKCOMWNQ-UHFFFAOYSA-N
Gene Information
human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), GSK3A(2931)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835)
General description
漆黄素是一种膳食黄酮类化合物，存在于多种水果和蔬菜中。它具有抗癌、抗炎、抗氧化活性，还具有记忆增强功能。
Application
漆黄素可用于：
- 制备其强抗氧化活性的铁金属配合物。
- 通过分析工具研究其与环糊精（α和β）的相互作用。
非瑟酮是一种天然存在的具有治疗活性的黄酮醇，用于合成具有药物活性的抗炎、抗惊厥和抗增殖药物。
Other Notes
存在于许多木本植物中的棕色颜料
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Giuseppe Sciamanna et al.
Cell reports, 31(7), 107644-107644 (2020-05-21)
Firing activity of external globus pallidus (GPe) is crucial for motor control and is severely perturbed in dystonia, a movement disorder characterized by involuntary, repetitive muscle contractions. Here, we show that GPe projection neurons exhibit a reduction of firing frequency
Xu Sun et al.
International journal of molecular medicine, 42(2), 811-820 (2018-05-12)
Fisetin, a natural flavonoid found in a variety of edible and medical plants, has been suggested to inhibit the proliferation of various tumor cells and to induce apoptosis. However, the effects of fisetin on breast cancer have rarely been reported
Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity.
Zheng, Long Tai and Ock, Jiyeon and Kwon, Byoung-Mog and Suk, Kyoungho
International Immunopharmacology, 8(3), 484-494 (2008)