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经验公式(希尔记法):
C15H10O6 · xH2O
化学文摘社编号:
分子量:
286.24 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
Colour Index Number:
75620
EC Number:
208-434-4
MDL number:
Beilstein/REAXYS Number:
292829
InChI key
GYHFUROKCOMWNQ-UHFFFAOYSA-N
InChI
1S/C15H10O6.H2O/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7;/h1-6,16-18,20H;1H2
SMILES string
O.Oc1ccc2C(=O)C(O)=C(Oc2c1)c3ccc(O)c(O)c3
assay
≥98%
mp
>330 °C (lit.)
storage temp.
−20°C
Gene Information
human ... CDC2(983), CDK5(1020), CDK6(1021), CYP1A2(1544), GSK3A(2931)
mouse ... Hexa(15211)
rat ... Il4(287287), Tnf(24835)
General description
漆黄素是一种膳食黄酮类化合物,存在于多种水果和蔬菜中。它具有抗癌、抗炎、抗氧化活性,还具有记忆增强功能。
Application
漆黄素可用于:
- 制备其强抗氧化活性的铁金属配合物。
- 通过分析工具研究其与环糊精(α和β)的相互作用。
非瑟酮是一种天然存在的具有治疗活性的黄酮醇,用于合成具有药物活性的抗炎、抗惊厥和抗增殖药物。
Other Notes
存在于许多木本植物中的棕色颜料
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Mohammed Alsuraih et al.
JHEP reports : innovation in hepatology, 3(3), 100250-100250 (2021-04-20)
Cholangiocyte senescence is important in the pathogenesis of primary sclerosing cholangitis (PSC). We found that CDKN2A (p16), a cyclin-dependent kinase inhibitor and mediator of senescence, was increased in cholangiocytes of patients with PSC and from a PSC mouse model (multidrug
Anti-inflammatory activity of structurally related flavonoids, Apigenin, Luteolin and Fisetin
Funakoshi-Tago M, et al.
International Immunopharmacology, 11(9), 1150-1159 (2011)
Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity.
Zheng, Long Tai and Ock, Jiyeon and Kwon, Byoung-Mog and Suk, Kyoungho
International Immunopharmacology, 8(3), 484-494 (2008)
Fisetin: a dietary antioxidant for health promotion
Khan N, et al.
Antioxidants & Redox Signaling, 19(2), 151-162 (2013)
Study of the complexation of fisetin with cyclodextrins
Guzzo MR, et al.
The Journal of Physical Chemistry A, 110(36), 10545-10551 (2006)
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