Merck
CN
所有图片(1)

文件

F6206

Sigma-Aldrich

4-氟苯磺酰氯

98%

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线性分子式:
FC6H4SO2Cl
CAS号:
349-88-2
分子量:
194.61
Beilstein:
2091633
EC 号:
206-493-0
MDL编号:
MFCD00007438
PubChem化学物质编号:
24894904
NACRES:
NA.22

质量水平

200

检测方案

98%

bp

95-96 °C/2 mmHg (lit.)

mp

29-31 °C (lit.)

SMILES string

Fc1ccc(cc1)S(Cl)(=O)=O

InChI

1S/C6H4ClFO2S/c7-11(9,10)6-3-1-5(8)2-4-6/h1-4H

InChI key

BFXHJFKKRGVUMU-UHFFFAOYSA-N

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相关类别

象形图

Corrosion
GHS05

警示用语：

Danger

危险声明

H314

危险分类

Skin Corr. 1B

储存分类代码

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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T H Liao et al.
Analytical biochemistry, 148(2), 365-375 (1985-08-01)
The reagent p-fluorobenzenesulfonyl chloride modifies the protein side chains of tyrosine, lysine, and histidine and the alpha-NH2 group. The p-fluorobenzenesulfonyl (Fbs-) group, identified by the 19F nuclear magnetic resonance signal, exhibits a different 19F chemical shift for each functional group
Y A Chang et al.
Bioconjugate chemistry, 3(2), 200-202 (1992-03-01)
4-Fluorobenzenesulfonyl chloride (fosyl chloride), due to the strong electron-withdrawing property of its fluoride atom, is found to be an excellent activating agent for the covalent attachment of biologicals to a variety of solid supports (e.g. functionalized polystyrene microspheres, Sepharose beads
Umaprasana Ojha et al.
Langmuir : the ACS journal of surfaces and colloids, 25(11), 6319-6327 (2009-04-02)
Peptide surface modification of poly[(methyl methacrylate-co-hydroxyethyl methacrylate)-b-isobutylene-b-(methyl methacrylate-co-hydroxyethyl methacrylate)] P(MMA-co-HEMA)-b-PIB-b-P(MMA-co-HEMA) triblock copolymers with different HEMA/MMA ratios has been accomplished using an efficient synthetic procedure. The triblock copolymers were reacted with 4-fluorobenzenesulfonyl chloride (fosyl chloride) in pyridine to obtain the activated
Ning Li et al.
European journal of medicinal chemistry, 155, 531-544 (2018-06-18)
Ten novel symmetric 3,5-bis(arylidene)-4-piperidone derivatives (BAPs, 1-10) and fourteen dissymmetric BAPs (11-24) were synthesized and evaluated the cytotoxicity. All of the compounds have been screened for their anti-inflammatory activity characterized by evaluating their inhibitory effects on LPS-induced IL-6, TNF-α secretion.
Abdelaziz Houmam et al.
Physical chemistry chemical physics : PCCP, 14(1), 113-124 (2011-09-15)
Important aspects of the electrochemical reduction of a series of substituted arene sulfonyl chlorides are investigated. An interesting autocatalytic mechanism is encountered where the starting material is reduced both at the electrode and through homogeneous electron transfer from the resulting

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