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Merck
CN

G10806

芦竹碱

97.5%

别名:

3-(二甲氨基甲基)吲哚, NSC 16892, 芦竹碱

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关于此项目

经验公式(希尔记法):
C11H14N2
化学文摘社编号:
分子量:
174.24
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-749-8
Beilstein/REAXYS Number:
140521
MDL number:
Assay:
97.5%
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InChI

1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3

InChI key

OCDGBSUVYYVKQZ-UHFFFAOYSA-N

SMILES string

CN(C)Cc1c[nH]c2ccccc12

assay

97.5%

Quality Level

mp

132-134 °C (lit.)

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Application

作为反应物用于制备:
  • 多巴胺D2受体拮抗剂
  • 抗疟疾药
  • 5-吲哚基-曼尼希碱
  • 增殖抑制剂
  • 人肥大细胞糜酶的抑制剂
  • DL-色氨酸的制备
  • 十字花科植物抗毒素黄铜素的潜在解毒抑制剂
  • 3-乙烯基吲哚
  • 血清素5-HT6受体配体模板
  • 选择性蛋白激酶cδ(PKCδ)下调因子

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

flash_point_f

332.6 °F

flash_point_c

167 °C

法规信息

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历史批次信息供参考:

分析证书(COA)

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E L Barker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(12), 4705-4717 (1999-06-15)
Mutation of a conserved Asp (D98) in the rat serotonin (5HT) transporter (rSERT) to Glu (D98E) led to decreased 5HT transport capacity, diminished coupling to extracellular Na+ and Cl-, and a selective loss of antagonist potencies (cocaine, imipramine, and citalopram
Jacob Owens et al.
Journal of the science of food and agriculture, 92(11), 2373-2378 (2012-03-21)
We hypothesized that eating a food containing saponins (SAP), or tannins (TAN) prior to foods containing the alkaloids gramine (GRA) or 5-methoxy-N,N-dimethyltryptamine (TRP) would provide benefits not possible when the alkaloid-containing foods were eaten alone. In Trial 1, four groups
P S Katz et al.
Journal of neurophysiology, 74(6), 2281-2294 (1995-12-01)
1. Neuromodulation has previously been shown to be intrinsic to the central pattern generator (CPG) circuit that generates the escape swim of the nudibranch mollusk Tritonia diomedea; the dorsal swim interneurons (DSIs) make conventional monosynaptic connections and evoke neuromodulatory effects
P Mayser et al.
Mycoses, 47(1-2), 34-39 (2004-03-05)
Reference as well as field strains of Malassezia furfur (30), M. sympodialis (49), M. globosa (52), M. obtusa (one), M. restricta (one), M. slooffiae (seven), and M. pachydermatis (373) were investigated for their ability to produce pigment and fluorochromes when
J Sartorius et al.
FEBS letters, 374(3), 387-392 (1995-11-06)
It is shown that NMR titrations can be used on a quantitative basis to derive binding constants and binding modes of ds-DNA ligand complexes from several signals. The results are partially at variance with literature conclusions; they can be interpreted

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