G10806
芦竹碱
97.5%
别名:
3-(二甲氨基甲基)吲哚, NSC 16892, 芦竹碱
质量水平
方案
97.5%
mp
132-134 °C (lit.)
SMILES字符串
CN(C)Cc1c[nH]c2ccccc12
InChI
1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3
InChI key
OCDGBSUVYYVKQZ-UHFFFAOYSA-N
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应用
作为反应物用于制备：
- 多巴胺D2受体拮抗剂
- 抗疟疾药
- 5-吲哚基-曼尼希碱
- 增殖抑制剂
- 人肥大细胞糜酶的抑制剂
- DL-色氨酸的制备
- 十字花科植物抗毒素黄铜素的潜在解毒抑制剂
- 3-乙烯基吲哚
- 血清素5-HT6受体配体模板
- 选择性蛋白激酶cδ（PKCδ）下调因子
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
332.6 °F
闪点(°C)
167 °C
法规信息
涉药品监管产品
此项目有
E L Barker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(12), 4705-4717 (1999-06-15)
Mutation of a conserved Asp (D98) in the rat serotonin (5HT) transporter (rSERT) to Glu (D98E) led to decreased 5HT transport capacity, diminished coupling to extracellular Na+ and Cl-, and a selective loss of antagonist potencies (cocaine, imipramine, and citalopram
P Mayser et al.
Mycoses, 47(1-2), 34-39 (2004-03-05)
Reference as well as field strains of Malassezia furfur (30), M. sympodialis (49), M. globosa (52), M. obtusa (one), M. restricta (one), M. slooffiae (seven), and M. pachydermatis (373) were investigated for their ability to produce pigment and fluorochromes when
J Sartorius et al.
FEBS letters, 374(3), 387-392 (1995-11-06)
It is shown that NMR titrations can be used on a quantitative basis to derive binding constants and binding modes of ds-DNA ligand complexes from several signals. The results are partially at variance with literature conclusions; they can be interpreted
P S Katz et al.
Journal of neurophysiology, 74(6), 2281-2294 (1995-12-01)
1. Neuromodulation has previously been shown to be intrinsic to the central pattern generator (CPG) circuit that generates the escape swim of the nudibranch mollusk Tritonia diomedea; the dorsal swim interneurons (DSIs) make conventional monosynaptic connections and evoke neuromodulatory effects
Robert M Williams et al.
Journal of the American Chemical Society, 125(40), 12172-12178 (2003-10-02)
The first total synthesis of paraherquamide A, a potent anthelmintic agent isolated from various Penicillium sp. with promising activity against drug-resistant intestinal parasites, is reported. Key steps in this asymmetric, stereocontrolled total synthesis include a new enantioselective synthesis of alpha-alkylated-beta-hydroxyproline
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