G4802
DL-甘油醛二聚体
95%
别名:
3,6-二羟基-1,4-二噁烷-2,5-二甲醇
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关于此项目
经验公式（希尔记法）:
C6H12O6
化学文摘社编号:
分子量:
180.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
95%
Quality Level
assay
95%
mp
144-145 °C (lit.)
storage temp.
2-8°C
SMILES string
OC[C@H]1O[C@@H](O)[C@H](CO)O[C@@H]1O
InChI
1S/2C3H6O3/c2*4-1-3(6)2-5/h2*1,3,5-6H,2H2
InChI key
NGNVWCSFFIVLAR-UHFFFAOYSA-N
General description
DL-甘油醛二聚物，是DL-甘油醛的二聚体形式，一种有机物晶体，由对称的p-二氧己环结构与环平面连接的羟基和羟甲基组成。在DL-丙氨酸衍生物的合成中，与一级烷基胺反应形成席夫碱。
Application
- 醛还原酶活性：以DL-甘油醛二聚体为底物，研究冬青卫矛叶子产出醛还原酶的酶促特性，解析醛糖的还原过程，对于了解植物胁迫反应有重要意义(Negm, 1986)。
- 还原酶功能：在人肝脏醛还原酶的纯化和鉴定中研究DL-甘油醛二聚体，着重它的代谢解毒作用，对于涉及药物代谢和毒性的应用有重要意义(Petrash and Srivastava, 1982)。
- 原生动物代谢通路：以DL-甘油醛二聚体为底物，研究束状带短膜虫(Crithidia fasciculata)产出的醛还原酶的酶促特性，解析原虫的代谢通路，对于开发抗寄生虫感染疗法有重要意义(Kobayashi, 1982)。
wgk
WGK 3
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Experimental and Theoretical Study of the Products from the Spontaneous Dimerization of DL-and D-Glyceraldehyde
Federico G, et al.
Journal of the Brazilian Chemical Society, 16, 467-476 (2005)
Non-enzymatic transformation of dl-glyceraldehyde, 1, 3-dihydroxyacetone, and pyruvaldehyde with primary amine to the same dl-alanine derivatives
Yande H, et al.
Tetrahedron Letters, 56, 4516-4519 (2015)
Chan Mee Lee et al.
Archives of pharmacal research, 38(6), 1090-1098 (2014-10-16)
Aldose reductase (AR) is a key enzyme in the polyol pathway that is strongly implicated in the pathogenesis of diabetic complications. AR inhibitors have been proposed as therapeutic agents for diabetic complications through suppression of sorbitol formation and accumulation. In
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| G4802-1G | 04061825590516 |
| G4802-5G | 04061831826838 |