G6805
乙醇醛二聚体
crystalline, mixture of stereoisomers. Melts between 80 and 90 °C depending on stereoisomeric composition
别名:
1,4-二噁烷-2,5-二醇, 2,5-二羟基-1,4-二噁烷, 羟基乙醛二聚体
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关于此项目
经验公式（希尔记法）:
C4H8O4
化学文摘社编号:
分子量:
120.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
506029
产品名称
乙醇醛二聚体, crystalline, mixture of stereoisomers. Melts between 80 and 90 °C depending on stereoisomeric composition
InChI
1S/C4H8O4/c5-3-1-7-4(6)2-8-3/h3-6H,1-2H2
SMILES string
OC1COC(O)CO1
InChI key
ATFVTAOSZBVGHC-UHFFFAOYSA-N
form
crystalline
Quality Level
mp
85 °C
storage temp.
2-8°C
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Application
乙醇醛二聚体可用于 3，4-二氮杂-2-己烯-1，6-二醇的合成，后者可经过氢化反应形成 1，2-双（2-羟乙基）肼。它在手性催化剂存在下与 2，3-二氢呋喃发生环加成反应，形成稠合的双环四氢呋喃 (bis-THF) 醇——一种 HIV 蛋白酶抑制剂的关键基团。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Efficient Synthesis of (3 R, 3a S, 6a R)-Hexahydrofuro [2, 3-b] furan-3-ol from Glycolaldehyde.
Canoy WL
Organic Letters, 10(6), 1103-1106 (2008)
Hiromi Niwa et al.
Journal of natural medicines, 75(1), 194-200 (2020-09-26)
The production and accumulation of advanced glycation end products (AGEs) have been implicated in diabetes and diabetic complication. This study was conducted as a search for an AGE inhibitor from brown alga, Sargassum macrocarpum. Separation and purification were performed using
1, 2-bis (2-hydroxyethyl) hydrazine and derivatives.
Nielsen AT
The Journal of Organic Chemistry, 42(17), 2900-2902 (1977)
Sander De Bruyne et al.
Journal of clinical medicine, 9(9) (2020-09-10)
Age-related macular degeneration is the leading cause of blindness in the developed world. Since advanced glycation end products (AGEs) are implicated in the pathogenesis of AMD through various lines of evidence, we investigated the potential of fructosamine-3-kinase (FN3K) in the
Stéphan Houdier et al.
Analytical and bioanalytical chemistry, 410(27), 7031-7042 (2018-08-11)
Derivatization techniques based on α-effect amines and H+ catalysis are commonly used for the measurement of carbonyl compounds (CCs), whether in environmental, food, or biological samples. Here, we investigated the potential of aniline-based catalysts to improve derivatization rates of selected
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