G7801
双甘肽
98%
别名:
二甘氨酸, 甘氨酰-甘氨酸
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关于此项目
线性分子式:
NH2CH2CONHCH2COOH
化学文摘社编号:
分子量:
132.12
EC Number:
209-127-8
UNSPSC Code:
12161700
PubChem Substance ID:
Beilstein/REAXYS Number:
1765223
MDL number:
InChI key
YMAWOPBAYDPSLA-UHFFFAOYSA-N
InChI
1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)
SMILES string
NCC(=O)NCC(O)=O
assay
98%
form
powder
useful pH range
7.5-8.9
pKa (25 °C)
8.2
mp
255-260 °C
application(s)
peptide synthesis
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Application
在生理 pH 值范围内可用的缓冲液。20°C 下的 pKa 为 8.40。用于肽建模和药物溶解研究。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Pharmazie, 48, 552-552 (1993)
M A Eiteman et al.
Biotechnology progress, 10(5), 513-519 (1994-09-01)
A mathematical procedure was developed to predict the partition coefficients of the peptides AIIP, AWWP, AIIPAIIP and AWWPAWWP in poly(ethylene glycol) (PEG)/phosphate aqueous two-phase systems from amino acid hydrophobicities. In general, peptides containing tryptophan partition more into the PEG-enriched upper
A Li et al.
Journal of pharmaceutical sciences, 83(12), 1735-1740 (1994-12-01)
The log-linear solubilization model was applied to the experimental solubility data of 109 organic compounds in ethanol/water mixtures. It is found that the extent of solubilization strongly depends on the solute hydrophobicity and the ethanol concentration in the solvent mixture.
Lasse Jenner et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(10), 3812-3816 (2013-02-23)
Here we present an X-ray crystallography structure of the clinically relevant tigecycline antibiotic bound to the 70S ribosome. Our structural and biochemical analysis indicate that the enhanced potency of tigecycline results from a stacking interaction with nucleobase C1054 within the
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 621-631 (2011-09-29)
We present a full computational description of the fragmentation reactions of protonated diglycine (H(+)GG). Relaxed potential energy surface scans performed at B3LYP/6-31 G(d) or B3LYP/6-311 + G(d,p) levels are used to map the reaction coordinate surfaces and identify the transition states (TSs) and
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