产品名称
Cationic Liposomes for DNA/RNA delivery, DDAB:Cholesterol (1:1) containing 0.5% NBD-DOPE (Fluorescent)
contains
NBD-DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-
1,3-benzoxadiazol-4-yl)) as fluorescent label
composition
Deionized RNAse-free Water
concentration
0.02 mM (NBD-DOPE)
2 mM (Cholesterol)
2 mM (DDAB)
impurities
1:1 mol/mol DDAB:Cholesterol
particle size
100 nm
pH
7
absorbance ratio
460/535 nm
Quality Level
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Legal Information
Application
Gene delivery
Lipid-protein interactions
Disclaimer
General description
Preparation Note
Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
商品
LNPs are ideal carriers for mRNA drugs, as evident from the two FDA-approved SARS-CoV-2 vaccines. However, efficient LNPs need further research on ionizable lipid selection, formulation, and administration. This review examines lipid usage, ionizable lipid selection, and LNP design for mRNA drug delivery.
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