H11904
2,5-己二醇
99% (mixture of isomers)
别名:
2,5-二羟基己烷
质量水平
方案
99% (mixture of isomers)
表单
liquid
折射率
n20/D 1.447 (lit.)
沸点
216-218 °C (lit.)
密度
0.961 g/mL at 25 °C (lit.)
SMILES字符串
CC(O)CCC(C)O
InChI
1S/C6H14O2/c1-5(7)3-4-6(2)8/h5-8H,3-4H2,1-2H3
InChI key
OHMBHFSEKCCCBW-UHFFFAOYSA-N
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应用
2,5-己二醇可用于：
- 作为反应剂与伯胺通过氧化偶联反应合成N-取代吡咯。
- 作为烷基化剂与吲哚经由Friedel-Crafts烷基化反应合成取代咔唑。
- 作为单体与二酸氯化物反应制备聚酯类物质。
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
213.8 °F - closed cup
闪点(°C)
101 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Corey Frazer et al.
Nature microbiology, 5(11), 1374-1389 (2020-07-29)
Cell identity in eukaryotes is controlled by transcriptional regulatory networks that define cell-type-specific gene expression. In the opportunistic fungal pathogen Candida albicans, transcriptional regulatory networks regulate epigenetic switching between two alternative cell states, 'white' and 'opaque', that exhibit distinct host
Lv Li et al.
Brain research, 1159, 8-17 (2007-06-19)
Opposing functions of activated microglia, namely neuroprotection or neurotrophy versus neurodestruction or neurotoxicity, have been observed in a number of experimental models of neurotrauma and neurodegenerative diseases. However, the mechanism(s) involved in the determination of which function activated microglia execute
P Nylén et al.
Archives of toxicology, 67(6), 435-441 (1993-01-01)
Albino (Sprague-Dawley) and pigmented (Norwegian Brown) male rats were exposed to 2,5-hexanediol (H; 1%) in their drinking water for 5 or 8 weeks, respectively. Half of the rats of each strain were housed in light (average 30 cd/cm2 inside cage
On the pattern of changes in the rat nervous system produced by 2,5 hexanediol. A topographical study by light microscopy.
J B Cavanagh et al.
Brain : a journal of neurology, 104(2), 297-318 (1981-06-01)
A K Agrawal et al.
Neurotoxicology, 6(3), 53-59 (1985-01-01)
Single exposure of 150, 300 and 600 mg/kg 2,5-hexanediol, (2,5 HD) a metabolite of n-hexane showed no significant effect on 3H-spiroperidol binding to corpus striatal membranes when compared with control animals, where as repeated exposure of 2,5-HD, 300 and 600
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