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Merck
CN

H125

骆驼蓬酚 盐酸盐 二水合物

monoamine oxidase inhibitor

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经验公式(希尔记法):
C12H12N2O · HCl · 2H2O
化学文摘社编号:
分子量:
272.73
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
227-898-9
MDL number:
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drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

mp

264-267 °C (dec.) (lit.)

SMILES string

Cl[H].[H]O[H].[H]O[H].CC1=NCCc2c1[nH]c3cc(O)ccc23

InChI

1S/C12H12N2O.ClH.2H2O/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12;;;/h2-3,6,14-15H,4-5H2,1H3;1H;2*1H2

InChI key

OYKGNQNESCZSHQ-UHFFFAOYSA-N

Biochem/physiol Actions

Harmalol, a harmala (β-carboline) alkaloid, is a monoamine oxidase inhibitor (MAOi) useful for studies involving melanogenesis. Harmalol is use in β-carboline nucleic acid (DNA and RNA) binding studies.


存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Ji-Hyun Im et al.
Vascular pharmacology, 50(5-6), 147-152 (2008-12-17)
Beta-carboline alkaloids including harmalol, harmaline, norharmane, harmol, harmine and harmane are important constituents of the medicinal plant, Perganum harmala L. (Zygophylaceae), which has been used in traditional medicine. In the present study, the antiplatelet activities of six beta-carboline alkaloid compounds
S Y Tse et al.
Biochemical pharmacology, 42(3), 459-464 (1991-07-15)
beta-Carboline alkaloids are derived as a result of condensation between indoleamine (e.g. tryptamine) and short-chain carboxylic acid (e.g. pyruvic acid) or aldehyde (e.g. acetaldehyde), a reaction that occurs readily at room temperature. These compounds have been found endogenously in human
Najma Arshad et al.
Phytotherapy research : PTR, 22(11), 1533-1538 (2008-09-25)
In the present study the antimicrobial potential of various extracts from 12 medicinal plants has been investigated in vitro on multiple antibiotic resistant pathogens and some selected protozoa isolated from poultry. The initial examination was performed on E. coli (n



全球贸易项目编号

货号GTIN
H125-5G-I04061833664742
H125-1G-A04061826675045
H125-100G-I04061833664728