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Merck
CN

H20008

间羟基苯甲酸

ReagentPlus®, 99%

别名:

水杨酸

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关于此项目

线性分子式:
HOC6H4CO2H
化学文摘社编号:
分子量:
138.12
Beilstein:
508160
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

产品线

ReagentPlus®

方案

99%

mp

200-203 °C (lit.)

SMILES字符串

OC(=O)c1cccc(O)c1

InChI

1S/C7H6O3/c8-6-3-1-2-5(4-6)7(9)10/h1-4,8H,(H,9,10)

InChI key

IJFXRHURBJZNAO-UHFFFAOYSA-N

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应用

3-羟基苯甲酸是各种生物活性小分子结构骨架的组成成分,可用于合成具有药用价值的化合物,如酪氨酸激酶Tie-2抑制剂、淀粉样蛋白生成抑制剂、抗氧化剂以及基于恶白藜芦醇的恶二唑类似物的抗炎剂。

法律信息

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Evolution of a highly selective and potent 2-(pyridin-2-yl)-1, 3, 5-triazine Tie-2 kinase inhibitor.
Hodous B L, et al.
Journal of Medicinal Chemistry, 50(4), 611-626 (2007)
Antioxidant and anti-inflammatory properties of 1, 2, 4-oxadiazole analogs of resveratrol.
Gobec M, et al.
Chemico-Biological Interactions, 240, 200-207 (2015)
Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
Johnson S M, et al.
Journal of Medicinal Chemistry, 51(2), 260-270 (2007)
Fredrik L Nordström et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 28(5), 377-384 (2006-06-20)
Solution and solid-state properties of m-hydroxybenzoic acid have been investigated. Two polymorphs were found where the monoclinic modification exhibits a higher stability than the orthorhombic form. The solubility of the monoclinic polymorph was determined between 10 and 50 degrees C
Stefania Montersino et al.
Biochimica et biophysica acta, 1824(3), 433-442 (2011-12-31)
The genome of Rhodococcus jostii RHA1 contains an unusually large number of oxygenase encoding genes. Many of these genes have yet an unknown function, implying that a notable part of the biochemical and catabolic biodiversity of this Gram-positive soil actinomycete

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