H31859
5-羟基苯并吡咯
97%
别名:
5-羟基吲哚, 5-羟基苯并吡咯, NSC 87503
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关于此项目
经验公式（希尔记法）:
C8H7NO
化学文摘社编号:
分子量:
133.15
Beilstein:
112349
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
质量水平
方案
97%
mp
106-108 °C (lit.)
SMILES字符串
Oc1ccc2[nH]ccc2c1
InChI
1S/C8H7NO/c10-7-1-2-8-6(5-7)3-4-9-8/h1-5,9-10H
InChI key
LMIQERWZRIFWNZ-UHFFFAOYSA-N
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应用
- 用于制备抗肿瘤剂（氧咪唑烷基/氧嘧啶基）苯磺酸酯和微管蛋白抑制剂的反应物
- 用于制备邻氨基苯甲酸的反应物
- 用于制备吲哚化合物作为多巴胺D2受体拮抗剂的反应物
- 用于制备含萘酰亚胺或咔唑的人β-肾上腺素受体配体的反应物
- 用于制备天然辐射防护剂黑色素的反应物
- 用于制备 PKCθ 抑制剂5-乙烯基-3-吡啶腈的反应物
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Ribosomal synthesis of cyclic peptides with a fluorogenic oxidative coupling reaction.
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David Robinson et al.
The journal of physical chemistry. B, 113(8), 2535-2541 (2009-02-07)
We have investigated the absorption and emission spectrum of 5-hydroxyindole in the gas phase and in various solvents. 5-Hydroxyindole is the fluorophore of the non-natural amino acid 5-hydroxytryptophan, which has attracted recent interest as a novel intrinsic probe for protein
Rui Shen Ong et al.
Drug testing and analysis, 12(2), 195-214 (2019-10-09)
We describe the validation of a method for the simultaneous analysis of 29 synthetic cannabinoids (SCs) and metabolites, 4 amphetamines, and 2 cannabinoids in human whole blood. This method enables one analysis to cover what previously required multiple analyses for
Uday Praful Kundap et al.
Pharmaceuticals (Basel, Switzerland), 13(6) (2020-05-30)
Epilepsy is a serious neurological disorder affecting around 70 million people globally and is characterized by spontaneous recurrent seizures. Recent evidence indicates that dysfunction in metabolic processes can lead to the alteration of neuronal and network excitability, thereby contributing to
Xiang-Qun Hu et al.
Neuropharmacology, 54(8), 1153-1165 (2008-04-26)
Allosteric modulation of ligand-gated ion channels can play important roles in shaping synaptic transmission. The function of the 5-hydroxytryptamine (serotonin) type 3 (5-HT(3)) receptor, a member of the Cys-loop ligand-gated ion channel superfamily, is modulated by a variety of compounds
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