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Merck
CN

H4392

3-羟基-3-甲基谷氨酸

≥95%

别名:

3-羟基-3-甲基戊二酸

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关于此项目

线性分子式:
HOC(CH3)(CH2CO2H)2
化学文摘社编号:
分子量:
162.14
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-971-1
Beilstein/REAXYS Number:
1769194
MDL number:
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产品名称

3-羟基-3-甲基谷氨酸, ≥95%

assay

≥95%

InChI key

NPOAOTPXWNWTSH-UHFFFAOYSA-N

InChI

1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10)

SMILES string

CC(O)(CC(O)=O)CC(O)=O

mp

105-108 °C (lit.)

storage temp.

−20°C

Quality Level

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Application

  • Improvement of the functional value of green soybean (edamame) using germination and tempe fermentation: A comparative metabolomics study.:该研究通过发芽和发酵技术挖掘毛豆更多的功能价值,发现多种代谢产物,包括3-羟基-3-甲基戊二酸。有助了解食品加工和营养生物化学(Iman et al., 2023)。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Beatriz Puisac et al.
Journal of inherited metabolic disease, 33(4), 405-410 (2010-06-10)
3-Hydroxy-3-methylglutaric aciduria is a rare human autosomal recessive disorder caused by deficiency of 3-hydroxy-3-methylglutaryl CoA lyase (HL). This mitochondrial enzyme catalyzes the common final step of leucine degradation and ketogenesis. Acute symptoms include vomiting, seizures and lethargy, accompanied by metabolic
Mohamad Eid Hammadeh et al.
American journal of reproductive immunology (New York, N.Y. : 1989), 47(2), 82-90 (2002-03-20)
The aims of the present study were to (i) determine the presence and concentration of albumin fractions (alpha1, alpha2, beta, gamma), immunoglobulins (IgA, IgG, IgM) and cytokines [interleukin (IL)-6, IL-8, granulocyte-macrophage colony-stimulating factor (GM-CSF)] in periovulatory ovarian follicular fluid (FF)
J Pie et al.
Journal of physiology and biochemistry, 59(4), 311-321 (2004-05-29)
3-Hydroxy-3-methylglutaric aciduria is a human autosomal recessive metabolic disorder that usually appears within the first year of life. The causes of this aciduria are lethal mutations in the gene encoding for 3-hydroxy-3-methylglutaryl coenzyme A lyase (HL). HL is a mitochondrial
Jan Frank et al.
The British journal of nutrition, 92(1), 169-176 (2004-07-03)
Secoisolariciresinol diglucoside (SDG) is an important dietary lignan that is found at very high levels in flaxseed (1-4 %, w/w). Flaxseed lignans have received much research interest in recent years because of reported phyto-oestrogenic, anticarcinogenic, and anti-atherogenic effects. Previously, flaxseed
Elaine A Porter et al.
Phytochemistry, 81, 90-96 (2012-06-23)
LC-UV-MS/MS analysis of leaf extracts from 146 accessions of 71 species of Rosa revealed that some taxa accumulated flavonol O-glycosides acylated with 3-hydroxy-3-methylglutaric acid, which are relatively uncommon in plants. The structures of two previously unrecorded examples isolated from Rosa

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