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文件

H4392

Sigma-Aldrich

3-羟基-3-甲基谷氨酸

≥95%

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别名:
3-羟基-3-甲基戊二酸
线性分子式:
HOC(CH3)(CH2CO2H)2
CAS号:
503-49-1
分子量:
162.14
Beilstein:
1769194
EC 号:
207-971-1
MDL编号:
MFCD00002712
PubChem化学物质编号:
57654253
NACRES:
NA.22

质量水平

200

检测方案

≥95%

mp

105-108 °C (lit.)

储存温度

−20°C

SMILES string

CC(O)(CC(O)=O)CC(O)=O

InChI

1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10)

InChI key

NPOAOTPXWNWTSH-UHFFFAOYSA-N

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相关类别

包装

无底玻璃瓶。内含物装在插入的融合锥内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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S Funghini et al.
Molecular genetics and metabolism, 73(3), 268-275 (2001-07-20)
3-Hydroxy-3-methylglutaric aciduria is a rare autosomal recessive inborn error of metabolism caused by deficiency of the mitochondrial enzyme 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL). Up to now only a few mutations have been reported in the HMGCL gene. We report the first Italian
Elaine A Porter et al.
Phytochemistry, 81, 90-96 (2012-06-23)
LC-UV-MS/MS analysis of leaf extracts from 146 accessions of 71 species of Rosa revealed that some taxa accumulated flavonol O-glycosides acylated with 3-hydroxy-3-methylglutaric acid, which are relatively uncommon in plants. The structures of two previously unrecorded examples isolated from Rosa
C Mir et al.
Journal of inherited metabolic disease, 29(1), 64-70 (2006-04-08)
3-Hydroxy-3-methylglutaric aciduria is a rare autosomal recessive genetic disorder that affects ketogenesis and leucine metabolism. The disease is caused by mutations in the gene coding for 3-hydroxy-3-methylglutaryl-coenzyme A lyase (HL). To date 26 different mutations have been described. A (betaalpha)(8)
Jan Frank et al.
The British journal of nutrition, 92(1), 169-176 (2004-07-03)
Secoisolariciresinol diglucoside (SDG) is an important dietary lignan that is found at very high levels in flaxseed (1-4 %, w/w). Flaxseed lignans have received much research interest in recent years because of reported phyto-oestrogenic, anticarcinogenic, and anti-atherogenic effects. Previously, flaxseed
Alister D Muir
Journal of AOAC International, 89(4), 1147-1157 (2006-08-19)
Flaxseed (Linum usitatissimum L.) is a major source of dietary intake of lignans by virtue of the high concentrations (0.7-1.5%) that are present in the seed. The principal lignan present in flaxseed is secoisolariciresinol diglucoside (SDG), which occurs as a
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