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Merck
CN

I18008

异哌啶酸

97%

别名:

4-哌啶甲酸, 六氢异烟酸

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关于此项目

经验公式(希尔记法):
C6H11NO2
化学文摘社编号:
分子量:
129.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
207-872-3
Beilstein/REAXYS Number:
112553
MDL number:
Assay:
97%
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Quality Level

assay

97%

mp

>300 °C (lit.)

SMILES string

OC(=O)C1CCNCC1

InChI

1S/C6H11NO2/c8-6(9)5-1-3-7-4-2-5/h5,7H,1-4H2,(H,8,9)

InChI key

SRJOCJYGOFTFLH-UHFFFAOYSA-N

Application

用于合成以下物质的反应物:
  • 用于组织蛋白酶 B 抑制的抗生素硝酰基衍生物
  • 1-磷酸鞘氨醇受体激动剂
  • 心血管疾病治疗的 RhoA 抑制剂
  • 烷基哌啶和哌嗪异羟肟酸作为 HDAC 抑制剂
  • CHK1 抑制剂
  • 用于类风湿性关节炎治疗研究的 IKK2 抑制剂


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jenna Elizabeth Hunt et al.
American journal of physiology. Gastrointestinal and liver physiology, 318(5), G980-G987 (2020-04-21)
Glucagon-like peptide (GLP)-1 and -2-secreting L cells have been shown to express the bile acid receptor Takeda G protein-receptor-5 (TGR5) and increase secretion upon receptor activation. Previous studies have explored GLP-1 secretion following acute TGR5 activation, but chronic activation and
Alicja Nowaczyk et al.
Journal of molecular graphics & modelling, 85, 171-181 (2018-09-17)
Inhibition of 4-aminobutanoic acid (GABA) uptake is a strategy for enhancing GABA transmission. The utility of this approach is demonstrated by the successful development of such agents for the treatment of epilepsy and pain. Existing reports on acute brain slice
Michela Semeraro et al.
Clinica chimica acta; international journal of clinical chemistry, 440, 108-112 (2014-12-03)
Pipecolic acid (PA) is an important biochemical marker for the diagnosis of peroxisomal disorders. PA is also a factor responsible for hepatic encephalopathy and a possible biomarker for pyridoxine-dependent seizures. We developed an easy and rapid PA quantification method, by



全球贸易项目编号

货号GTIN
I18008-25G04061833848111
I18008-100G04061838354808