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线性分子式:
C8H14O8 · NH3
化学文摘社编号:
分子量:
255.22
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
产品名称
2-酮基-3-脱氧辛烷 铵盐, ≥97%
InChI
1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3
SMILES string
N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O
InChI key
UDJBBKGYARWWNJ-UHFFFAOYSA-N
assay
≥97%
form
powder
storage temp.
−20°C
Quality Level
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Biochem/physiol Actions
KDO 是一种唾液酸,是细菌脂多糖的成分以及抗生素研发的可用靶标。
Application
- KDO类似物的合成:研究3-脱氧-D-甘露-辛酮糖酸(KDO)类似物的合成,包括2-酮基-3-脱氧辛酮酸铵盐。这些类似物是CMP-KDO合成酶的潜在抑制剂,对于开发治疗细菌感染的新药十分重要,有助于加强对细菌脂多糖合成的了解(Luthman et al., 1987)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Campylobacter jejuni outer membrane vesicles (OMVs) contain numerous virulence-associated proteins including the cytolethal distending toxin and three serine proteases. As C. jejuni lacks the classical virulence-associated secretion systems of other enteric pathogens that deliver effectors directly into target cells, OMVs
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Aloka B Bandara et al.
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Francisella tularensis is a category-A select agent and is responsible for tularemia in humans and animals. The surface components of F. tularensis that contribute to virulence are not well characterized. An electron-dense capsule has been postulated to be present around
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Microbial pathogenesis, 152, 104738-104738 (2021-02-03)
Lipopolysaccharide (LPS) is the major surface antigen of Leptospira. In this study, the genes involved in the LPS biosynthesis were analyzed and compared by bioinformatics tools. Also, the chemical composition analysis of leptospiral lipopolysaccharides (LPS) extracted from 5 pathogenic serovars
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