K6000
α-酮-γ-甲硫基丁酸 钠盐
≥97%
别名:
4-甲硫基-2-氧丁酸 钠盐, 4-甲硫基-2-氧代丁酸 钠盐, KMBA
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关于此项目
线性分子式:
C5H7O3SNa
化学文摘社编号:
分子量:
170.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥97%
Quality Level
assay
≥97%
storage temp.
2-8°C
SMILES string
[Na].CSCCC(=O)C(O)=O
InChI
1S/C5H8O3S.Na/c1-9-3-2-4(6)5(7)8;/h2-3H2,1H3,(H,7,8);/q;+1/p-1
InChI key
IFSCKRWNXKWTLR-UHFFFAOYSA-M
General description
α-酮-γ-甲硫丁酸(KMTB)是L-甲硫氨酸的酮衍生物，作为L-甲硫氨酸的替代物具有较大潜力。KMTB的钠盐可用于亲核取代反应。还可作为合成砌块制备氨基酸、多肽等复杂有机物。
Application
- 采用ORAC和TOSC法测定抗氧化能力。本研究详细介绍了α-酮-γ(甲硫基)丁酸钠盐在ORAC和TOSC测定法评估抗氧化能力中的应用，强调了其在代谢和化学合成研究中的作用（Garrett AR et al., 2010）。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
D R Livingstone et al.
Marine environmental research, 50(1-5), 57-60 (2001-07-20)
The present study investigated the proposed involvement of contaminant-stimulated reactive oxygen species (ROS) production in disease processes in fish. NAD(P)H-dependent ROS production of subcellular fractions was determined by the iron/EDTA-mediated oxidation of 2-keto-4-methiolbutyric acid. Hepatic cytosolic NADPH-dependent and microsomal NAD(P)H-dependent
Z Findrik et al.
Biotechnology and bioengineering, 98(5), 956-967 (2007-05-31)
D-Methionine was converted to L-methionine in a reaction system where four enzymes were used. D-amino acid oxidase (D-AAO) from Arthrobacter protophormiae was used for the complete conversion of D-methionine to 2-oxo-4-methylthiobutyric acid. Catalase was added to prevent 2-oxo-4-methylthiobutyric acid decarboxylation.
Baiqing Tang et al.
Biochemical pharmacology, 72(7), 806-815 (2006-07-28)
4-Methylthio-2-oxobutanoic acid (MTOB) is the final compound of the methionine salvage pathway that converts the polyamine byproduct methylthioadenosine to adenine and methionine. Here we find that MTOB inhibits growth of several human cell lines in a dose-dependent manner. Growth inhibition
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| K6000-10MG | 04061832621371 |
| K6000-1G | 04061825927145 |
| K6000-100MG | 04061832621364 |
| K6000-500MG | 04061832621388 |