L031200
活化剂42®溶液
0.3 M
别名:
5- [3,5-双（三氟甲基）苯基] -1 H-四唑溶液, 5- [3,5-双（三氟甲基）苯基] -2 H-四唑溶液
产品名称
活化剂42®溶液, 0.3 M
color
clear
Quality Level
SMILES string
FC(F)(F)c1cc(cc(c1)c2n[nH]nn2)C(F)(F)F
InChI
1S/C9H4F6N4/c10-8(11,12)5-1-4(7-16-18-19-17-7)2-6(3-5)9(13,14)15/h1-3H,(H,16,17,18,19)
InChI key
KKJFZIQEWZVVIV-UHFFFAOYSA-N
type
for DNA synthesis
product line
Proligo Reagents
storage condition
dry at room temperature
concentration
84-92 g/L (Activator 42 content, titration)
impurities
≤30 ppm water content (Karl Fischer)
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Other Notes
Activator solution, containing 5-(3,5-bis(trifluoromethyl)phenyl)-1H-tetrazole (Activator 42) in acetonitrile, are mixed with solutions of phosphoramidites during the extension step.
The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.
The activator reacts with the amidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′hydroxyl group of the growing oligonucleotide chain.
Preparation Note
Acetronitrile / Activator 42 100 / 9 (v/w)
Legal Information
Activator 42 is a registered trademark of Sigma-Aldrich Co. LLC
本产品及其用途涵盖于美国专利号 7,897,758 中
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
41.0 °F
flash_point_c
5 °C
法规信息
危险化学品
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