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Merck
CN

L040080

Cap A

configured for PerkinElmer, configured for Polygen

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关于此项目

NACRES:
NA.21
UNSPSC Code:
12352200
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type

for DNA synthesis

Quality Level

product line

Proligo Reagents

form

liquid

storage condition

dry at room temperature

concentration

88.7-108.4 g/L (Acetic Anhydride content, titration)

color

clear

compatibility

configured for PerkinElmer, configured for Polygen

General description

Cap A solution contains acetic anhydride and tetrahydrofuran (THF). It is used after the phosphoramidite reaction/coupling step.

Biochem/physiol Actions

Cap A solution aborts chains bearing unreacted 5′ hydroxyl groups due to failure of reaction with activated phosphoramidite (typically, 1 to 2% of growing oligonucleotide chains in each synthesis cycle). These unreacted 5′ hydroxyl groups are capped with an acetyl group and thus rendered unreactive for subsequent synthesis steps.

Preparation Note

乙酸酐/四氢呋喃 9.1/90.9 (v/v)


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Central nervous system, Respiratory system

supp_hazards

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

-6.2 °F - closed cup

flash_point_c

-21.2 °C - closed cup

法规信息

易制毒化学品(2类)
危险化学品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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全球贸易项目编号

货号GTIN
L040080-4X2L04061838215970
L040080-6X200ML04061838215987
L040080-4L04061838215956
L040080-2.5L04061838215949
L040080-4X2.5L04061838215963
L040080-45L04061837443305
L040080-6X450ML04061838215994