L091000
N,N-二甲基甲酰胺
别名:
DMF, NSC 5356
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线性分子式:
HCON(CH3)2
化学文摘社编号:
分子量:
73.09
UNSPSC Code:
12352111
NACRES:
NA.51
PubChem Substance ID:
EC Number:
200-679-5
Beilstein/REAXYS Number:
605365
MDL number:
Bp:
153 °C (lit.)
Vapor pressure:
2.7 mmHg ( 20 °C)
InChI key
ZMXDDKWLCZADIW-UHFFFAOYSA-N
InChI
1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
SMILES string
[H]C(=O)N(C)C
vapor density
2.5 (vs air)
vapor pressure
2.7 mmHg ( 20 °C)
type
for DNA synthesis
product line
Proligo Reagents
form
liquid
autoignition temp.
833 °F
expl. lim.
15.2 %
storage condition
dry at room temperature
impurities
≤200 ppm water content (Karl Fischer)
≤9 ppm Amine content
color
clear
refractive index
n20/D 1.430 (lit.)
pH
6.7
bp
153 °C (lit.)
mp
−61 °C (lit.)
density
0.944 g/mL (lit.)
Quality Level
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Application
多种疏水性有机化合物的溶剂。
DMF is a widely used polar solvent in which organic, organometallic, and bioorganic transformations are carried out. It is also a solvent for many hydrophobic organic compounds and acts as a source of building blocks in various organic synthesis reactions.
General description
N,N-Dimethylformamide (DMF) is an amide that works as a multipurpose reagent that is an effective polar solvent for various compounds and a ligand for metallic compounds. It also acts as a key intermediate as an electrophilic or nucleophilic agent for mediating reactions as it delivers its own H, C, N, and O atoms in compound synthesis.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
存储类别
3 - Flammable liquids
wgk
WGK 2
flash_point_f
135.5 °F - closed cup
flash_point_c
57.5 °C - closed cup
法规信息
新产品
此项目有
N,N-Dimethylformamide: much more than a solvent
Jacques Muzart
Tetrahedron, 65, 8313?8323-8313?8323 (2009)
Recent Uses of N, N-Dimethylformamide and N, N-Dimethylacetamide as Reagents
Jean Le Bras, Jacques Muzart
Molecules (Basel), 23(8) (2018)
A Journey from June 2018 to October 2021 with N, N-Dimethylformamide and N, N-Dimethylacetamide as Reactants
Jacques Muzart
Molecules (Basel), 26(21) (2021)
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