M10050
3-甲氧基苯甲酰胺
97%
别名:
间茴香酰胺
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关于此项目
线性分子式:
CH3OC6H4CONH2
化学文摘社编号:
分子量:
151.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
227-379-7
Beilstein/REAXYS Number:
2206857
MDL number:
Assay:
97%
InChI key
VKPLPDIMEREJJF-UHFFFAOYSA-N
InChI
1S/C8H9NO2/c1-11-7-4-2-3-6(5-7)8(9)10/h2-5H,1H3,(H2,9,10)
SMILES string
COc1cccc(c1)C(N)=O
assay
97%
mp
132.5-135.5 °C (lit.)
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
B C Waldman et al.
Biochimica et biophysica acta, 1308(3), 241-250 (1996-09-11)
Inhibition of poly(ADP-ribosylation) reduces random genomic integration of transfected DNA and mildly stimulates intrachromosomal homologous recombination in mammalian cells. We investigated the effect of inhibition of poly(ADP-ribosylation) on the efficiency of gene targeting in Chinese hamster ovary (CHO) cell line
R C Tasker et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 18(12), 1346-1356 (1998-12-16)
In the infant brain, ischemia-induced ionic and enzyme mechanisms may independently lead to cell death by energy depletion: resequestration of calcium mobilized from intracellular stores consumes ATP, and activated poly(ADP-ribose) polymerase (PARP) uses oxidized nicotinamide adenine dinucleotide to form polyADP-ribosyl
T Tsujiuchi et al.
Carcinogenesis, 11(10), 1783-1787 (1990-10-01)
The effects of inhibitors of poly(ADP-ribose)polymerase, 3-aminobenzamide (ABA), luminol and 3-methoxybenzamide (MBA) on the rat liver tumor promotion activity of phenobarbital (PB) were assessed. Fischer 344 male rats were initiated with N-nitrosodiethylamine (200 mg/kg) and placed on either basal diet
S Hauschildt et al.
Advances in experimental medicine and biology, 419, 249-252 (1997-01-01)
Stimulating monocytes/macrophages with bacterial lipopolysaccharide (LPS) results in TNF-alpha, IL-1, IL-6 and nitrite (NO2-) formation. Inhibitors of poly(ADP-ribose)polymerase inhibit release of these mediators by preventing mRNA expression indicating that ADP-ribosylation plays a crucial role in the synthesis of these mediators.
G Golderer et al.
The Biochemical journal, 277 ( Pt 3), 607-610 (1991-08-01)
ADP-ribosylation of core histones was investigated in isolated nuclei of Physarum polycephalum. Core histone species differed in the mode of modification. Whereas ADP-ribosylation of H2A and H2B is sensitive to inhibition by 3-methoxybenzamide, as with most other nuclear acceptor proteins
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