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Merck
CN

N21804

Sigma-Aldrich

3-硝基苯肼 盐酸盐

98%

别名:

1-(3-硝基苯基)肼盐酸盐, 3-硝基苯肼单盐酸盐, 3-硝基苯肼盐酸盐, 间硝基苯肼盐酸盐

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关于此项目

线性分子式:
O2NC6H4NHNH2 · HCl
化学文摘社编号:
分子量:
189.60
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

98%

表单

powder

mp

210 °C (dec.) (lit.)

SMILES字符串

Cl.NNc1cccc(c1)[N+]([O-])=O

InChI

1S/C6H7N3O2.ClH/c7-8-5-2-1-3-6(4-5)9(10)11;/h1-4,8H,7H2;1H

InChI key

BKOYKMLGFFASBG-UHFFFAOYSA-N

一般描述

3-硝基苯肼 (3-NPH)是一种衍生化试剂,用于含羧基 和羰基代谢产物的衍生化。该化合物也用作 高效的化学同位素标记试剂。此外,3-硝基苯肼 可与取代苯甲醛通过缩合反应 形成一系列10取代(E)-1-苯亚甲基-2-(3-硝基苯) 肼化合物。

应用

<ul>
<li><strong>分析化学中的衍生化剂:</strong>利用LC-MRM-MS技术,将3-硝基苯基肼盐酸盐用作衍生化剂,用于检测感染单纯疱疹病毒1型的生物样品中的γ -羟基丁酸,从而增强法医和临床毒理学的检测能力(Osinaga等人,2022)。</li>
<li><strong>药物配方中的残留分析:</strong>该化合物还可用于氯霉素及其制剂中残留的4-硝基苯甲醛的定量分析,采用3-硝基苯肼衍生化后的高效液相色谱-紫外/可见检测,为保证药品的纯度和安全性提供了可靠的方法(Luo et al., 2018)。</li>
<li><strong>法医在分解分析中的应用:</strong>用于衍生化法医尸检时采集的血液样本(Matoba et al., 2022)。</li>
</ul>

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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