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经验公式(希尔记法):
C15H12O5
化学文摘社编号:
分子量:
272.25
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
266-769-1
MDL number:
产品名称
(±)-柚皮素, ≥95%
InChI key
FTVWIRXFELQLPI-UHFFFAOYSA-N
InChI
1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
SMILES string
OC1=CC=C(C=C1)C(C2)OC3=CC(O)=CC(O)=C3C2=O
assay
≥95%
form
powder
mp
247-250 °C (lit.)
Quality Level
Gene Information
human ... CYP1A2(1544)
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Application
(±)-柚皮素是一种多酚材料,可用于制备镍(II)柚皮素-肟配合物,该配合物可作为催化剂用于Mizoroki−Heck交叉偶联反应。它已用作次氯酸盐清除剂,以防止人血清白蛋白中次氯酸盐氧化形成氯胺。它可诱导人胰腺癌SNU-213细胞的凋亡。它还显示出对多种人类癌细胞(如乳腺癌、宫颈癌、胃癌、结肠癌和肝癌细胞)的细胞毒性作用。
wgk
WGK 1
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Hypochlorite scavenging activity of flavonoids
Firuzi O, et al.
The Journal of Pharmacy and Pharmacology, 56(6), 801-807 (2004)
Efficient nickel (ii) naringenin-oxime complex catalyzed Mizoroki-Heck cross-coupling reaction in the presence of hydrazine hydrate
Song JY, et al.
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Inhibitory effects of naringenin on tumor growth in human cancer cell lines and sarcoma S-180-implanted mice
Kanno S, et al.
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商品
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子(如铁、铜和镉)引起的氧化损伤。
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