P0256
吡啶硫胺 氢溴酸盐
~95%, crystalline
别名:
1-([4-氨基-2-甲基]-5-嘧啶基甲基)-2-甲基-3-(β-羟乙基)溴化吡啶鎓, 新吡啶硫胺
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关于此项目
经验公式（希尔记法）:
C14H18N4O · 2HBr
化学文摘社编号:
分子量:
420.14
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
208-604-8
MDL number:
Assay:
~95%
Form:
crystalline
assay
~95%
Quality Level
form
crystalline
color
off-white to yellow
storage temp.
2-8°C
SMILES string
Br.[Br-].Cc1ncc(C[n+]2cccc(CCO)c2C)c(N)n1
InChI
1S/C14H19N4O.2BrH/c1-10-12(5-7-19)4-3-6-18(10)9-13-8-16-11(2)17-14(13)15;;/h3-4,6,8,19H,5,7,9H2,1-2H3,(H2,15,16,17);2*1H/q+1;;/p-1
InChI key
DMVBWVASDWGFNH-UHFFFAOYSA-M
General description
吡啶硫胺氢溴酸盐是一种杂环化合物合成砌块，由于能够模拟硫胺素缺乏症且可能用于开发具有实用药理特性的新化合物，因而成为重要的有机合成和药物化学工具。
Application
吡啶硫胺氢溴酸盐可用作合成焦磷酸吡硫胺的前体。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Xiaohua He et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 32(10), 2207-2216 (2007-02-15)
The relative roles of alcohol and thiamine deficiency in causing brain damage remain controversial in alcoholics without the Wernicke-Korsakoff syndrome. Experimental control over alcohol consumption and diet are impossible in humans but can be accomplished in animal models. This experiment
Stéphane Thore et al.
Science (New York, N.Y.), 312(5777), 1208-1211 (2006-05-06)
Riboswitches are untranslated regions of messenger RNA, which adopt alternate structures depending on the binding of specific metabolites. Such conformational switching regulates the expression of proteins involved in the biosynthesis of riboswitch substrates. Here, we present the 2.9 angstrom-resolution crystal
Jessica J Roland et al.
Neurobiology of learning and memory, 87(1), 123-132 (2006-09-19)
A rodent model of diencephalic amnesia, pyrithiamine-induced thiamine deficiency (PTD), was used to investigate the dynamic role of hippocampal and striatal acetylcholine (ACh) efflux across acquisition of a nonmatching-to-position (NMTP) T-maze task. Changes in ACh efflux were measured in rats
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P0256-1MG | 04061826677490 |
| P0256-10MG | 04061834290902 |
| P0256-5MG | 04061834290919 |